SCHEMBL12840351

SCHEMBL12840351

CCc1nc(-c2ccccc2)cnc1NC(=O)CCc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.47
GAA P10253 1/20 0.47
ADORA3 P0DMS8 1/20 0.46
ADORA2A P29274 1/20 0.46
HTT P42858 2/20 0.46
LMNA P02545 2/20 0.45
TSHR P16473 2/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
RAB9A P51151 3/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
HSD17B10 Q99714 1/20 0.45
ROCK2 O75116 1/20 0.45
ADORA1 P30542 1/20 0.44
GSK3B P49841 2/20 0.44
NPC1 O15118 2/20 0.44
GSK3A P49840 1/20 0.44
WNT1 P04628 1/20 0.44
DYRK1A Q13627 1/20 0.44
CYP2C9 P11712 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12838911 0.93 HCAR2 (0.50) MAPTGAAHTTLMNATSHR
SCHEMBL12840352 0.93 NPC1 (0.50) MAPTGAAADORA3ADORA2ARAB9A
SCHEMBL12839162 0.92 HCAR2 (0.47) MAPTGAAADORA3ADORA2AHTT
SCHEMBL12838961 0.90 MAPT (0.47) MAPTGAAADORA3LMNATSHR
SCHEMBL12839935 0.90 ADORA3 (0.48) MAPTGAAADORA3ADORA2AHTT
SCHEMBL12840367 0.88 TMIGD3 (0.52) TSHRRAB9AMEN1KMT2AHSD17B10
SCHEMBL12838908 0.87 TRPV1 (0.52) MAPTGAATSHRRAB9AMEN1
SCHEMBL12840499 0.86 NPC1 (0.46) MAPTGAARAB9AMEN1KMT2A
SCHEMBL12839155 0.86 LMNA (0.46) GAAADORA3ADORA2ALMNARAB9A
SCHEMBL12838481 0.85 HCAR2 (0.49) MAPTGAAHTTLMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110070656-A1 Fluorescent Proteins JNC CORPORATION (JP) 2011-03-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110070656-A1 Fluorescent Proteins CACYBP, CHLSN, LCP2 MAPT 3847/4885GAA 1256/4885ADORA3 3943/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.