SCHEMBL12840388

SCHEMBL12840388

O=C(Cc1ccc(I)cc1)Nc1ncc(-c2ccc(O)cc2)nc1CCc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DEGS1 O15121 1/20 0.44
MEN1 O00255 5/20 0.43
KMT2A Q03164 5/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
MAPK1 P28482 1/20 0.42
TMIGD3 P0DMS9 1/20 0.41
MTOR P42345 1/20 0.41
GLS O94925 1/20 0.41
CYP2C8 P10632 1/20 0.40
CYP2C9 P11712 1/20 0.40
HCAR2 Q8TDS4 1/20 0.40
TRPV1 Q8NER1 1/20 0.40
ELOVL1 Q9BW60 1/20 0.39
ROCK1 Q13464 1/20 0.39
PRKDC P78527 1/20 0.39
ATM Q13315 1/20 0.39
ATR Q13535 1/20 0.39
BCHE P06276 1/20 0.39
ACHE P22303 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2508250 0.95 DEGS1 (0.48) DEGS1MEN1KMT2ANPC1RAB9A
SCHEMBL13068208 0.94 TMIGD3 (0.47) DEGS1MEN1KMT2ANPC1RAB9A
SCHEMBL12838875 0.94 DEGS1 (0.49) DEGS1MEN1KMT2ANPC1RAB9A
SCHEMBL12840498 0.91 GLS (0.41) MEN1KMT2ANPC1RAB9ATMIGD3
SCHEMBL12839145 0.91 MAPK14 (0.45) MEN1KMT2ANPC1RAB9ATMIGD3
SCHEMBL12838890 0.91 DEGS1 (0.45) DEGS1MEN1KMT2ANPC1RAB9A
SCHEMBL12840400 0.90 DEGS1 (0.44) DEGS1MEN1KMT2ANPC1RAB9A
SCHEMBL12840399 0.90 KMT2A (0.46) DEGS1MEN1KMT2ANPC1RAB9A
SCHEMBL12840398 0.90 KMT2A (0.45) DEGS1MEN1KMT2ANPC1RAB9A
SCHEMBL12839144 0.90 KMT2A (0.45) DEGS1MEN1KMT2ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110070656-A1 Fluorescent Proteins JNC CORPORATION (JP) 2011-03-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110070656-A1 Fluorescent Proteins CACYBP, CHLSN, LCP2 DEGS1 4476/4885MEN1 3926/4885KMT2A 4653/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.