Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22689608 | 0.86 | TDP1 (0.45) | TDP1ALOX15TSHRALDH1A1LMNA | |
| SCHEMBL2530412 | 0.82 | — | — | |
| SCHEMBL9756912 | 0.81 | TDP1 (0.48) | TDP1ALOX15TSHRALDH1A1LMNA | |
| SCHEMBL11619041 | 0.80 | ALOX15 (0.58) | TDP1ALOX15TSHRALDH1A1LMNA | |
| SCHEMBL15542591 | 0.80 | PTPN1 (0.42) | TDP1ALOX15TSHRALDH1A1LMNA | |
| SCHEMBL8336829 | 0.80 | TDP1 (0.41) | TDP1ALOX15TSHRALDH1A1LMNA | |
| SCHEMBL1985053 | 0.80 | ALDH1A1 (0.44) | TDP1ALOX15TSHRALDH1A1LMNA | |
| SCHEMBL25342022 | 0.78 | ALDH1A1 (0.42) | TDP1ALOX15TSHRALDH1A1LMNA | |
| SCHEMBL19248370 | 0.78 | ALDH1A1 (0.42) | TDP1ALOX15TSHRALDH1A1LMNA | |
| SCHEMBL28994092 | 0.78 | TDP1 (0.39) | TDP1ALOX15TSHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1982986-B1 | PYRROLOPYRIDAZINONE COMPOUND AS PDE4 INHIBITOR | UBE INDUSTRIES (JP) | 2012-03-07 | — | — | EP | disclosed |