Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | CRHBP | P24387 | 1/20 | 0.55 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.51 |
| ▸ | PRNP | P04156 | 2/20 | 0.51 |
| ▸ | F10 | P00742 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14136957 | 0.92 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2KMT2ARAB9APKM | |
| SCHEMBL12767900 | 0.86 | MAPT (0.69) | ALDH1A1SMN1; SMN2KMT2ARAB9ATDP1 | |
| SCHEMBL14706510 | 0.83 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2KMT2ARAB9ATDP1 | |
| SCHEMBL14096502 | 0.77 | ALDH1A1 (0.72) | ALDH1A1SMN1; SMN2KMT2ARAB9ATDP1 | |
| SCHEMBL31321777 | 0.75 | ALDH1A1 (0.85) | ALDH1A1SMN1; SMN2KMT2ARAB9ATDP1 | |
| SCHEMBL11955716 | 0.74 | F10 (0.55) | SMN1; SMN2KMT2ARAB9AMAPTNPC1 | |
| SCHEMBL2526384 | 0.73 | RXFP1 (0.49) | ALDH1A1SMN1; SMN2KMT2ARAB9ATDP1 | |
| SCHEMBL12767872 | 0.73 | KMT2A (0.72) | ALDH1A1SMN1; SMN2KMT2ARAB9ATDP1 | |
| SCHEMBL584871 | 0.72 | RXFP1 (0.71) | ALDH1A1KMT2APKMNPSR1MAPT | |
| SCHEMBL29939764 | 0.72 | RXFP1 (0.71) | ALDH1A1KMT2APKMNPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110065704-A1 | COMPOUNDS FOR MODULATING RNA BINDING PROTEINS AND USES THEREFOR | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110065704-A1 | COMPOUNDS FOR MODULATING RNA BINDING PROTEINS AND USES THEREFOR | TIA1, ZFP3, RBM3 | ALDH1A1 3135/4885SMN1; SMN2 2721/4885KMT2A 3013/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.