Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.72 |
| ▸ | MAPT | P10636 | 13/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.72 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.71 |
| ▸ | PRNP | P04156 | 2/20 | 0.71 |
| ▸ | NPC1 | O15118 | 3/20 | 0.66 |
| ▸ | RAB9A | P51151 | 3/20 | 0.66 |
| ▸ | GAA | P10253 | 3/20 | 0.66 |
| ▸ | PKM | P14618 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.65 |
| ▸ | MEN1 | O00255 | 6/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | RECQL | P46063 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12767900 | 0.92 | MAPT (0.69) | ALDH1A1MAPTKDM4ERXFP1SMN1; SMN2 | |
| SCHEMBL13956784 | 0.87 | PRSS12 (0.64) | ALDH1A1MAPTKDM4ERXFP1SMN1; SMN2 | |
| SCHEMBL5464660 | 0.86 | MAPT (0.67) | ALDH1A1MAPTKDM4ERXFP1SMN1; SMN2 | |
| SCHEMBL5935569 | 0.86 | MAPT (0.79) | ALDH1A1MAPTKDM4ERXFP1SMN1; SMN2 | |
| SCHEMBL14136957 | 0.84 | ALDH1A1 (0.56) | ALDH1A1MAPTKDM4ERXFP1SMN1; SMN2 | |
| SCHEMBL12767889 | 0.84 | MAPT (1.00) | ALDH1A1MAPTKDM4ERXFP1SMN1; SMN2 | |
| SCHEMBL13956777 | 0.82 | MEN1 (0.58) | ALDH1A1MAPTKDM4ERXFP1SMN1; SMN2 | |
| SCHEMBL13956806 | 0.82 | ALDH1A1 (0.57) | ALDH1A1MAPTKDM4ERXFP1SMN1; SMN2 | |
| SCHEMBL13956800 | 0.81 | MAPT (0.58) | ALDH1A1MAPTKDM4ERXFP1SMN1; SMN2 | |
| SCHEMBL13956812 | 0.81 | MAPT (0.53) | ALDH1A1MAPTKDM4ERXFP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207760-A1 | Pharmaceutical Compositions For and Methods of Inhibiting Hcv | ACHILLION PHARMACEUTICALS, INC. (US) | 2008-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207760-A1 | Pharmaceutical Compositions For and Methods of Inhibiting Hcv | RNASE1, SARS1, EIF2AK2 | ALDH1A1 2930/4885MAPT 4038/4885KDM4E 3665/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.