Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | RAB9A | P51151 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | CRHBP | P24387 | 1/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | PRNP | P04156 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12767900 | 0.83 | MAPT (0.69) | ALDH1A1KMT2ARAB9ASMN1; SMN2TDP1 | |
| SCHEMBL12840765 | 0.83 | ALDH1A1 (0.55) | ALDH1A1KMT2ARAB9ASMN1; SMN2TDP1 | |
| SCHEMBL14096502 | 0.74 | ALDH1A1 (0.72) | ALDH1A1KMT2ARAB9ASMN1; SMN2TDP1 | |
| SCHEMBL14136957 | 0.74 | ALDH1A1 (0.56) | ALDH1A1KMT2ARAB9ASMN1; SMN2PKM | |
| SCHEMBL13806635 | 0.74 | MCL1 (0.58) | ALDH1A1KMT2AMAPTPRNPKDM4E | |
| SCHEMBL31321777 | 0.73 | ALDH1A1 (0.85) | ALDH1A1KMT2ARAB9ASMN1; SMN2TDP1 | |
| SCHEMBL11955716 | 0.71 | F10 (0.55) | KMT2ARAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL11517919 | 0.68 | ALDH1A1 (1.00) | ALDH1A1KMT2ARAB9ASMN1; SMN2TDP1 | |
| SCHEMBL12768389 | 0.68 | ALDH1A1 (0.71) | ALDH1A1KMT2ARAB9ASMN1; SMN2TDP1 | |
| SCHEMBL5464660 | 0.67 | MAPT (0.67) | ALDH1A1KMT2ARAB9ASMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8377639-B2 | Compounds for modulating RNA binding proteins and uses therefor | UNIVERSITY OF MASSACHUSETTS (US) | 2013-02-19 | — | — | US | disclosed |