Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 3/20 | 0.33 |
| ▸ | NOS1 | P29475 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12841667 | 0.91 | HRH4 (0.37) | SMN1; SMN2KMT2AL3MBTL1HPGDCYP1A2 | |
| SCHEMBL12842028 | 0.86 | KDM4E (0.37) | MEN1KMT2AHTR2ASCN8ASRC | |
| SCHEMBL12841895 | 0.86 | PRKCQ (0.38) | L3MBTL1HTR2AALDH1A1SCN8APDE10A | |
| SCHEMBL19937086 | 0.85 | NOS3 (0.33) | NOS3NOS1SMN1; SMN2HTR2ASCN8A | |
| SCHEMBL12841856 | 0.85 | SMN1; SMN2 (0.42) | NOS3NOS1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL12841907 | 0.84 | LOXL2 (0.39) | SMN1; SMN2MEN1KMT2AL3MBTL1HPGD | |
| SCHEMBL12841912 | 0.83 | KDM4E (0.46) | SMN1; SMN2MEN1KMT2AL3MBTL1HPGD | |
| SCHEMBL12842054 | 0.82 | CHEK1 (0.37) | SMN1; SMN2MEN1KMT2AL3MBTL1HPGD | |
| SCHEMBL12772513 | 0.82 | CDK1 (0.35) | NOS3NOS1SMN1; SMN2HTR2AAR | |
| SCHEMBL7215762 | 0.82 | L3MBTL1 (0.37) | SMN1; SMN2MEN1KMT2AL3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7897778-B2 | Benzamide compounds | ASTRAZENECA (SE) | 2011-03-01 | — | — | US | disclosed |
| US-20080293687-A1 | Benzamide Compounds | ASTRAZENECA AB (SE) | 2008-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293687-A1 | Benzamide Compounds | HDAC1, HDAC11, HDAC2 | NOS3 1041/4885NOS1 915/4885SMN1; SMN2 1455/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.