Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY6 | Q15077 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
| ▸ | HTR3B | O95264 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.37 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 2/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 9/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LTA | P01374 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.34 |
| ▸ | RAD51 | Q06609 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20258489 | 0.83 | HTR3E (0.42) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL1435515 | 0.80 | P2RY6 (0.38) | P2RY6CA1CA2HTR3EHTR3B | |
| SCHEMBL30673506 | 0.80 | P2RY6 (0.38) | P2RY6CA1CA2HTR3EHTR3B | |
| SCHEMBL27973968 | 0.79 | P2RY6 (0.37) | P2RY6CA1CA2HTR3EHTR3B | |
| SCHEMBL881834 | 0.79 | HTR3E (0.56) | P2RY6HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL13813270 | 0.79 | P2RY6 (0.37) | P2RY6CA1CA2HTR3EHTR3B | |
| SCHEMBL18084255 | 0.78 | FFAR4 (0.40) | CA1CA2HTR3EHTR3BHTR3A | |
| SCHEMBL13153135 | 0.77 | P2RY6 (0.45) | P2RY6CA1CA2MIFPNMT | |
| SCHEMBL13788639 | 0.76 | KIF11 (0.41) | P2RY6CA1CA2HTR3EHTR3B | |
| SCHEMBL16906398 | 0.76 | MAPT (0.52) | CA2HTR3EHTR3BHTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110077581-A1 | TARGETED CELLULAR DELIVERY OF NANOPARTICLES | GEORGIA TECH RESEARCH CORPORATION (US) | 2011-03-31 | — | — | US | disclosed |
| WO-2010099238-A1 | SPECIFIC DIARYLHYDANTOIN AND DIARYLTHIOHYDANTOIN COMPOUNDS | MEDIVATION PROSTATE THERAPEUTICS, INC. (US) | 2010-09-02 | — | — | WO | disclosed |