Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.56 |
| ▸ | HTR3B | O95264 | 1/20 | 0.56 |
| ▸ | HTR3A | P46098 | 1/20 | 0.56 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.56 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.56 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 7/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NPFFR2 | Q9Y5X5 | 3/20 | 0.39 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.39 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.37 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11287987 | 0.86 | HTR3E (0.40) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL23270232 | 0.84 | HTR3E (0.44) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL23270208 | 0.84 | AR (0.47) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL58303 | 0.82 | MAPK1 (0.61) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL29397209 | 0.82 | MAPK1 (0.61) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL15563090 | 0.81 | CA1 (0.45) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL23270216 | 0.81 | HTR3E (0.44) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL30543083 | 0.81 | CA1 (0.45) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL30543087 | 0.81 | CA1 (0.45) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL1435515 | 0.80 | P2RY6 (0.38) | HTR3EHTR3BHTR3AHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160250175-A1 | COMBINED APPLICATION OF ISOTHIOCYANATE COMPOUND AND ANTI-CANCER MEDICINE | JC (WUXI) COMPANY, INC. (CN) | 2016-09-01 | — | — | US | claimed |
| EP-3034076-A1 | COMBINED APPLICATION OF ISOTHIOCYANATE COMPOUND AND ANTI-CANCER MEDICINE | JC (Wuxi) COMPANY, Inc. (CN) | 2016-06-22 | — | — | EP | claimed |
| CN-103992265-B | Two three bromo 1,3-bis-pyridine alkali propane and preparation method thereof, using method, recovery method and application | XI'AN JIAOTONG UNIVERSITY (CN) | 2016-02-24 | — | — | CN | claimed |
| CN-103992265-A | Double tribromo 1,3-bipyridine onium salt dimethylmethane, and preparation method, application method, recovery method and application thereof | UNIV XI AN JIAOTONG | 2014-08-20 | — | — | CN | claimed |
| US-20250216398-A1 | IDENTIFICATION OF AMINO ACIDS OR SHORT PEPTIDES | LUXEMBOURG INSTITUTE OF SCIENCE AND TECHNOLOGY (LIST) (LU) | 2025-07-03 | — | — | US | disclosed |
| US-20250197443-A1 | METHOD AND DEVICE FOR CLEAVING AND/OR SEQUENCING A PEPTIDE | LUXEMBOURG INSTITUTE OF SCIENCE AND TECHNOLOGY (LIST) (LU) | 2025-06-19 | — | — | US | disclosed |
| EP-4493934-A1 | METHOD AND DEVICE FOR CLEAVING AND/OR SEQUENCING A PEPTIDE | LUXEMBOURG INSTITUTE OF SCIENCE AND TECHNOLOGY (LIST) (LU) | 2025-01-22 | — | — | EP | disclosed |
| EP-3446689-B1 | ISOTHIOCYANATE COMPOUND FOR USE IN THE TREATMENT OF HYPERBILIRUBINEMIA | JC WUXI COMPANY INC (CN) | 2025-01-08 | — | — | EP | disclosed |
| CN-113262218-B | Use of isothiocyanate compounds | 无锡杰西医药股份有限公司 | 2024-06-18 | — | — | CN | disclosed |
| WO-2023174860-A1 | IDENTIFICATION OF AMINO ACIDS OR SHORT PEPTIDES | LUXEMBOURG INSTITUTE OF SCIENCE AND TECHNOLOGY (LIST) (LU) | 2023-09-21 | — | — | WO | disclosed |
| WO-2023174823-A1 | METHOD AND DEVICE FOR CLEAVING AND/OR SEQUENCING A PEPTIDE | LUXEMBOURG INSTITUTE OF SCIENCE AND TECHNOLOGY (LIST) (LU) | 2023-09-21 | — | — | WO | disclosed |
| US-20230265075-A1 | 6-HETEROARYLOXY BENZIMIDAZOLES AND AZABENZIMIDAZOLES AS JAK2 INHIBITORS | AJAX THERAPEUTICS, INC. | 2023-08-24 | — | — | US | disclosed |
| US-5814646-A | TREATING THE PROGRESSION OF ALZHEIMER'S DISEASE, BRAIN DISORDERS | ELI LILLY AND COMPANY (US) | 1998-09-29 | — | — | US | disclosed |
| US-5760066-A | AIDS, ATHEROSCLEROSIS, CANCER | SUGEN, INC. (US) | 1998-06-02 | — | — | US | disclosed |
| US-5624937-A | TREATMENT OF ALZHEIMER'S DISEASE | ELI LILLY AND COMPANY (US) | 1997-04-29 | — | — | US | disclosed |
| WO-1996033179-A1 | THIOAMIDES DERIVATES AND THEIR USE AS INHIBITORS OF HYPER-PROLIFERATIVE CELL GROWTH | SUGEN, INC. (US) | 1996-10-24 | — | — | WO | disclosed |
| US-5399565-A | Treatment of psychological, central nervous system and gastrointestinal disorders | ELI LILLY AND COMPANY (US) | 1995-03-21 | — | — | US | disclosed |
| US-5300514-A | Pyrazolidinone CCK and gastrin antagonists and pharmaceutical formulations thereof | ELI LILLY AND COMPANY (US) | 1994-04-05 | — | — | US | disclosed |
| US-4913722-A | HERBICIDES | ICI AMERICAS INC. (US) | 1990-04-03 | — | — | US | disclosed |
| EP-0318253-A1 | Iminophenylthiazolidines, process of preparation, and method of use | ICI AMERICAS INC. (US) | 1989-05-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160250175-A1 | COMBINED APPLICATION OF ISOTHIOCYANATE COMPOUND AND ANTI-CANCER MEDICINE | CHUK, KIT, MKI67 | HTR3E 2361/4885HTR3B 2360/4885HTR3A 3106/4885 |
| US-20250197443-A1 | METHOD AND DEVICE FOR CLEAVING AND/OR SEQUENCING A PEPTIDE | ANPEP, DNPEP, PTMS | HTR3E 1555/4885HTR3B 1439/4885HTR3A 3191/4885 |
| US-20230265075-A1 | 6-HETEROARYLOXY BENZIMIDAZOLES AND AZABENZIMIDAZOLES AS JAK2 INHIBITORS | JAK2, JAK3, STAT5B | HTR3E 926/4885HTR3B 514/4885HTR3A 1337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.