Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.54 |
| ▸ | GRM5 | P41594 | 1/20 | 0.52 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.50 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.46 |
| ▸ | NNMT | P40261 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 4/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | CCR8 | P51685 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8385558 | 0.82 | ASIC3 (0.61) | ASIC3GRM5PIK3CDPIK3C3NNMT | |
| SCHEMBL12843365 | 0.79 | FEN1 (0.53) | ASIC3GRM5PIK3CDPIK3C3NNMT | |
| SCHEMBL10293127 | 0.76 | ASIC3 (0.51) | ASIC3GRM5PIK3CDPIK3C3NNMT | |
| SCHEMBL8385317 | 0.75 | ASIC3 (0.57) | ASIC3GRM5PIK3CDPIK3C3NNMT | |
| SCHEMBL8388712 | 0.73 | ASIC3 (0.62) | ASIC3GRM5PIK3CDPIK3C3NNMT | |
| SCHEMBL14147612 | 0.73 | ASIC3 (0.55) | ASIC3GRM5PIK3CDPIK3C3NNMT | |
| SCHEMBL10293323 | 0.73 | ASIC3 (0.62) | ASIC3GRM5PIK3CDPIK3C3NNMT | |
| SCHEMBL8389157 | 0.73 | ASIC3 (0.58) | ASIC3GRM5PIK3CDPIK3C3NNMT | |
| SCHEMBL8385495 | 0.72 | ASIC3 (0.57) | ASIC3GRM5PIK3CDPIK3C3NNMT | |
| SCHEMBL1011236 | 0.71 | ASIC3 (0.49) | ASIC3HTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110059963-A1 | COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR | PLEXXIKON, INC. | 2011-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110059963-A1 | COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR | MAP3K20, MAP3K13, MAP3K8 | ASIC3 4358/4885GRM5 4037/4885PIK3CD 139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.