Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 5/20 | 0.53 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.53 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.51 |
| ▸ | GRM5 | P41594 | 1/20 | 0.50 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.47 |
| ▸ | NNMT | P40261 | 2/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | QPCT | Q16769 | 1/20 | 0.38 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10293127 | 0.82 | ASIC3 (0.51) | FEN1ALOX5APASIC3GRM5PIK3C3 | |
| SCHEMBL8385558 | 0.80 | ASIC3 (0.61) | FEN1ALOX5APASIC3GRM5PIK3C3 | |
| SCHEMBL12843362 | 0.79 | ASIC3 (0.54) | FEN1ALOX5APASIC3GRM5PIK3C3 | |
| SCHEMBL27466773 | 0.74 | DRD2 (0.54) | PIK3CDIDO1MAPKAPK2QPCTQPCTL | |
| SCHEMBL31359591 | 0.73 | ALDH1A1 (0.40) | FEN1ALOX5APGRM5IDO1CHEK1 | |
| SCHEMBL27682801 | 0.73 | ALDH1A1 (0.43) | FEN1ALOX5APIDO1CHEK1QPCT | |
| SCHEMBL8385317 | 0.73 | ASIC3 (0.57) | FEN1ALOX5APASIC3GRM5PIK3C3 | |
| SCHEMBL21573715 | 0.72 | NNMT (0.57) | FEN1ALOX5APASIC3GRM5PIK3C3 | |
| SCHEMBL10293323 | 0.71 | ASIC3 (0.62) | FEN1ALOX5APASIC3GRM5PIK3C3 | |
| SCHEMBL8388712 | 0.71 | ASIC3 (0.62) | FEN1ALOX5APASIC3GRM5PIK3C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110059963-A1 | COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR | PLEXXIKON, INC. | 2011-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110059963-A1 | COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR | MAP3K20, MAP3K13, MAP3K8 | FEN1 2321/4885ALOX5AP 4050/4885ASIC3 4358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.