Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | EIF4E | P06730 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 2/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 2/20 | 0.39 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29878607 | 0.86 | MAPT (0.50) | MAPTEIF4EALDH1A1TDP1AR | |
| SCHEMBL12844122 | 0.84 | EIF4E (0.41) | MAPTEIF4EALDH1A1KIF11POLB | |
| SCHEMBL12844120 | 0.82 | EIF4E (0.44) | MAPTEIF4EALDH1A1TDP1AR | |
| SCHEMBL12777196 | 0.79 | MAPT (0.49) | MAPTALDH1A1TDP1CRHBPCRHR2 | |
| SCHEMBL27915252 | 0.79 | AKR1C3 (0.52) | ALDH1A1TDP1ARFFAR4AKR1C3 | |
| SCHEMBL27542162 | 0.78 | EIF4E (0.42) | EIF4EALDH1A1TDP1ARKIF11 | |
| SCHEMBL29655194 | 0.77 | BACE1 (0.47) | MAPTEIF4EALDH1A1TDP1AR | |
| SCHEMBL2311283 | 0.77 | MAPT (0.58) | MAPTEIF4EALDH1A1TDP1AR | |
| SCHEMBL27463044 | 0.77 | ALDH1A1 (0.54) | EIF4EALDH1A1TDP1ARKIF11 | |
| SCHEMBL28907766 | 0.75 | CASP6 (0.44) | MAPTEIF4EALDH1A1TDP1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110053939-A1 | NOVEL AROMATIC NITRO COMPOUNDS | REVOTAR BIOPHARMACEUTICALS AG (DE) | 2011-03-03 | — | — | US | disclosed |
| US-7851501-B2 | Aromatic nitrocatechol compounds and their use for modulating processes mediated by cell adhesion molecules | REVOTAR BIOPHARMACEUTICALS AG (DE) | 2010-12-14 | — | — | US | disclosed |
| US-7851501-B2 | Aromatic nitrocatechol compounds and their use for modulating processes mediated by cell adhesion molecules | REVOTAR BIOPHARMACEUTICALS AG (DE) | 2010-12-14 | — | — | US | disclosed |
| US-20090105280-A1 | Novel Aromatic Nitro Compounds | REVOTAR BIOPHARMACEUTICALS AG (DE) | 2009-04-23 | — | — | US | disclosed |
| US-20090105280-A1 | Novel Aromatic Nitro Compounds | REVOTAR BIOPHARMACEUTICALS AG (DE) | 2009-04-23 | — | — | US | disclosed |
| WO-2007039114-A1 | NOVEL NITROCATECHOL DERIVATIVES HAVING SELECTIN LIGAND ACTIVITY | REVOTAR BIOPHARMACEUTICALS AG (DE) | 2007-04-12 | — | — | WO | disclosed |
| EP-1764095-A1 | Novel nitrocatechol derivatives having selectin ligand activity | Revotar Biopharmaceuticals AG (DE) | 2007-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105280-A1 | Novel Aromatic Nitro Compounds | SELP, SELE, SELL | MAPT 2781/4885EIF4E 3484/4885ALDH1A1 215/4885 |
| US-20110053939-A1 | NOVEL AROMATIC NITRO COMPOUNDS | SELP, SELE, SELL | MAPT 2781/4885EIF4E 3484/4885ALDH1A1 215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.