Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | HTR3A | P46098 | 1/20 | 0.30 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2076641 | 0.84 | PDE9A (0.34) | HTR3AHRH4 | |
| SCHEMBL12845042 | 0.83 | FLT3 (0.30) | — | |
| SCHEMBL13061238 | 0.77 | PIK3CA (0.35) | — | |
| SCHEMBL13061258 | 0.74 | NOS3 (0.34) | HTR3AHRH4 | |
| SCHEMBL2078591 | 0.70 | MAPT (0.38) | — | |
| SCHEMBL13061508 | 0.67 | KDM4E (0.34) | — | |
| SCHEMBL2077826 | 0.65 | PDE9A (0.39) | — | |
| SCHEMBL2076738 | 0.65 | PDE9A (0.35) | — | |
| SCHEMBL2302147 | 0.64 | PDE9A (0.39) | — | |
| SCHEMBL2077472 | 0.64 | PDE9A (0.35) | HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110053920-A1 | SUBSTITUTED BICYCLIC PYRIMIDINES | CEPHALON, INC. (US) | 2011-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110053920-A1 | SUBSTITUTED BICYCLIC PYRIMIDINES | DPYD, P2RX5, P2RX7 | GRIN2B 361/4885HTR3A 485/4885HRH4 613/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.