Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1679837 | 0.84 | TSHR (0.57) | TSHRPPARDTP53TDP1MEN1 | |
| SCHEMBL1679770 | 0.84 | TSHR (0.57) | TSHRPPARDTP53TDP1MEN1 | |
| SCHEMBL16681891 | 0.84 | TSHR (0.57) | TSHRPPARDTP53TDP1MEN1 | |
| SCHEMBL11341590 | 0.77 | TSHR (0.50) | TSHRPPARDTP53TDP1MEN1 | |
| SCHEMBL4609885 | 0.77 | TSHR (0.50) | TSHRPPARDTP53TDP1MEN1 | |
| SCHEMBL20490115 | 0.77 | TSHR (0.50) | TSHRPPARDTP53TDP1MEN1 | |
| SCHEMBL1378158 | 0.77 | TSHR (0.55) | TSHRPPARDTP53TDP1MEN1 | |
| SCHEMBL874362 | 0.76 | TSHR (0.48) | TSHRPPARDTP53TDP1MEN1 | |
| SCHEMBL11443334 | 0.76 | TSHR (0.48) | TSHRPPARDTP53TDP1MEN1 | |
| SCHEMBL9208492 | 0.74 | TSHR (0.46) | TSHRPPARDTP53TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8324427-B2 | Substances analogous to MK8383 and agricultural and horticultural disease control agents | MEIJI SEIKA KAISHA, LTD. (JP) | 2012-12-04 | — | — | US | disclosed |
| US-20110065792-A1 | NOVEL SUBSTANCES ANALOGOUS TO MK8383 AND AGRICULTURAL AND HORTICULTURAL DISEASE CONTROL AGENTS | MEIJI SEIKA KAISHA, LTD. (JP) | 2011-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110065792-A1 | NOVEL SUBSTANCES ANALOGOUS TO MK8383 AND AGRICULTURAL AND HORTICULTURAL DISEASE CONTROL AGENTS | TSG101, PPME1, DDT | TSHR 4148/4885TRPA1 1406/4885PPARD 4007/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.