SCHEMBL12846147

SCHEMBL12846147

CCc1cnc(=O)[nH]c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29068210 0.83 NPC1 (0.35)
SCHEMBL8603815 0.78 PNP (0.34)
SCHEMBL14424070 0.78 MEN1 (0.38)
SCHEMBL5988807 0.74 GABRA1 (0.46)
Hydrochloric Acid SCHEMBL20958707 0.71 CHRNB2 (0.32)
SCHEMBL312460 0.70
SCHEMBL17572657 0.69 LYN (0.54)
SCHEMBL5751212 0.69 CYP1A2 (0.45)
SCHEMBL22002706 0.68 NPC1 (0.34)
SCHEMBL16518823 0.67 NPC1 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116964196-A Recombinant oncolytic virus and medical application thereof 深圳艾欣达伟医药科技有限公司 2023-10-27 CN disclosed
WO-2023205468-A1 HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN VERTEX PHARMACEUTICALS INCORPORATED (US) 2023-10-26 WO disclosed
US-20230059865-A1 METHODS AND COMPOSITIONS FOR MODULATING SPLICING SKYHAWK THERAPEUTICS, INC. 2023-02-23 US disclosed
US-20230025130-A1 METHODS FOR MODULATING SPLICING SKYHAWK THERAPEUTICS, INC. 2023-01-26 US disclosed
US-20230011652-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY NOVARTIS AG (CH) 2023-01-12 US disclosed
US-20220403383-A1 METHODS AND COMPOSITIONS FOR MODULATING SPLICING SKYHAWK THERAPEUTICS, INC. 2022-12-22 US disclosed
US-11326165-B1 Methods and compositions for modulating splicing SKYHAWK THERAPEUTICS, INC. (US) 2022-05-10 US disclosed
US-11162101-B2 Methods and compositions for modulating splicing SKYHAWK THERAPEUTICS, INC. (US) 2021-11-02 US disclosed
US-11129829-B2 Methods for modulating splicing SKYHAWK THERAPEUTICS, INC. (US) 2021-09-28 US disclosed
US-11021708-B2 Methods and compositions for modulating splicing SKYHAWK THERAPEUTICS, INC. (US) 2021-06-01 US disclosed
US-20200390765-A1 METHODS FOR MODULATING SPLICING SKYHAWK THERAPEUTICS, INC. 2020-12-17 US disclosed
US-20200247799-A1 METHODS AND COMPOSITIONS FOR MODULATING SPLICING SKYHAWK THERAPEUTICS, INC. 2020-08-06 US disclosed
US-20200224199-A1 METHODS AND COMPOSITIONS FOR MODULATING SPLICING SKYHAWK THERAPEUTICS, INC. 2020-07-16 US disclosed
EP-2880033-B1 CYCLIC UREA- OR LACTAM-SUBSTITUTED QUINOXALINE-TYPE PIPERIDINE COMPOUNDS AND THE USES THEREOF PURDUE PHARMA LP (US) 2020-06-17 EP disclosed
WO-2019012001-A1 MICROBIOCIDAL OXADIAZOLE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2019-01-17 WO disclosed
US-7897601-B2 Cannabinoid receptor modulators INTERVET, INC. (US) 2011-03-01 US disclosed
EP-1481077-B1 MITOTIC KINESIN INHIBITORS MERCK & CO INC (US) 2009-11-04 EP disclosed
EP-1458726-B1 MITOTIC KINESIN INHIBITORS MERCK & CO INC (US) 2009-07-15 EP disclosed
EP-1551812-B1 MITOTIC KINESIN INHIBITORS MERCK & CO INC (US) 2009-03-04 EP disclosed
US-7244723-B2 Substituted furopyrimidinones as a mitotic kinesin inhibitors MERCK & CO., INC. (US) 2007-07-17 US disclosed