Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.34 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.34 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10735778 | 0.90 | MAPT (0.44) | ALDH1A1CYP1A2GFERDYRK1AKDM4E | |
| SCHEMBL3936459 | 0.87 | HTR2A (0.43) | ALDH1A1CYP1A2GFERDYRK1ACYP1A1 | |
| SCHEMBL13980469 | 0.87 | CYP1A2 (0.41) | ALDH1A1CYP1A2GFERDYRK1ACYP1A1 | |
| SCHEMBL10729669 | 0.87 | CYP1A2 (0.41) | ALDH1A1CYP1A2GFERDYRK1ACYP3A4 | |
| SCHEMBL32671766 | 0.81 | ACHE (0.46) | ALDH1A1GFERDYRK1AKDM4ETSHR | |
| SCHEMBL29208987 | 0.81 | MAPT (0.42) | ALDH1A1GFERDYRK1ASMN1; SMN2CYP3A4 | |
| SCHEMBL23796848 | 0.78 | KDM4E (0.43) | ALDH1A1CYP1A2KDM4ETSHRSMN1; SMN2 | |
| SCHEMBL30031802 | 0.78 | KDM4E (0.43) | ALDH1A1CYP1A2KDM4ETSHRSMN1; SMN2 | |
| SCHEMBL2945602 | 0.78 | ALDH1A1 (0.48) | ALDH1A1CYP1A2CYP1A1CYP1B1KDM4E | |
| SCHEMBL20817223 | 0.76 | ALDH1A1 (0.46) | ALDH1A1CYP1A2CYP1A1CYP1B1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110053276-A1 | MOLECULAR INDICATOR AND PROCESS OF SYNTHESIZING | BATTELLE MEMORIAL INSTITUTE | 2011-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110053276-A1 | MOLECULAR INDICATOR AND PROCESS OF SYNTHESIZING | MUS81, MKI67, AOC1 | ALDH1A1 173/4885CYP1A2 2315/4885GFER 681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.