Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 3/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12794242 | 0.81 | KAT7 (0.39) | ALDH1A1CYP3A4MAPTHPGDSMN1; SMN2 | |
| SCHEMBL1108476 | 0.78 | CALM1 (0.44) | TAAR1ALDH1A1HPGDSMN1; SMN2TDP1 | |
| SCHEMBL12875431 | 0.74 | HSD17B10 (0.51) | ALDH1A1USP2MAPTKMT2AHSD17B10 | |
| SCHEMBL30000562 | 0.73 | TAAR1 (0.60) | TAAR1IDO1DAOALDH1A1MAPK1 | |
| SCHEMBL29459538 | 0.73 | TAAR1 (0.60) | TAAR1IDO1DAOALDH1A1MAPK1 | |
| SCHEMBL1263547 | 0.73 | TAAR1 (0.60) | TAAR1IDO1DAOALDH1A1MAPK1 | |
| SCHEMBL30638836 | 0.72 | CYP2C19 (0.60) | TAAR1FYNCYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL21142106 | 0.72 | CYP2C19 (0.60) | TAAR1FYNCYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL20313307 | 0.70 | TAAR1 (0.44) | TAAR1FYNIDO1DAOCYP2D6 | |
| SCHEMBL11899073 | 0.70 | HTR2C (0.43) | TAAR1IDO1DAOALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110053931-A1 | QUINOLINE COMPOUNDS AND METHODS OF USE | GAUDINO JOHN | 2011-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110053931-A1 | QUINOLINE COMPOUNDS AND METHODS OF USE | TK1, ABL1, ROR1 | TAAR1 501/4885FYN 415/4885IDO1 1283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.