SCHEMBL12848645

SCHEMBL12848645

CCC(C)Cc1c(N)c(N)c(CC(C)C)c(N)c1N

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 1/20 0.30
TLR7 Q9NYK1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12848649 0.77 HCAR2 (0.30)
SCHEMBL20226618 0.76 TLR8 (0.30) TLR8TLR7
SCHEMBL5186990 0.73 TSHR (0.35)
SCHEMBL20223449 0.73
SCHEMBL12848646 0.73 GABRA1 (0.32) TLR8TLR7
SCHEMBL12848648 0.71 GABRA1 (0.38) TLR8TLR7
SCHEMBL20226519 0.69 USP2 (0.33)
SCHEMBL22351911 0.68 NOS3 (0.32)
SCHEMBL27698451 0.68 CYP3A4 (0.37) TLR8TLR7
SCHEMBL12848647 0.67 GABRA1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7902547-B2 Thin-film transistor, electro-optical device, and electronic apparatus SEIKO EPSON CORPORATION (JP) 2011-03-08 US disclosed
US-20090146138-A1 THIN-FILM TRANSISTOR, ELECTRO-OPTICAL DEVICE, AND ELECTRONIC APPARATUS SEIKO EPSON CORPORATION (JP) 2009-06-11 US disclosed