Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5506106 | 0.82 | — | — | |
| SCHEMBL17207644 | 0.82 | DPP4 (0.35) | DPP4DPP8DPP9DPP7BTK | |
| SCHEMBL26599781 | 0.82 | DPP4 (0.35) | DPP4DPP8DPP9DPP7BTK | |
| SCHEMBL26599785 | 0.82 | DPP4 (0.35) | DPP4DPP8DPP9DPP7BTK | |
| SCHEMBL19722718 | 0.77 | DPP4 (0.37) | DPP4DPP8DPP9DPP7ATM | |
| Trifluoroacetic Acid SCHEMBL26599376 | 0.75 | DPP4 (0.33) | DPP4DPP8DPP9DPP7BTK | |
| SCHEMBL14589116 | 0.75 | — | — | |
| SCHEMBL24629359 | 0.74 | ACHE (0.34) | DPP4DPP8DPP9DPP7BTK | |
| SCHEMBL12548838 | 0.74 | DPP4 (0.38) | DPP4DPP8DPP9DPP7BTK | |
| SCHEMBL5949432 | 0.74 | DPP4 (0.38) | DPP4DPP8DPP9DPP7ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012126084-A1 | HSP-90 BINDING COMPOUNDS, COMPOSITIONS THEREOF, AND THEIR USE IΝ THE TREATMENT AND PREVENTION OF FUNGAL INFECTIONS | PHARMASCIENCE INC. (CA) | 2012-09-27 | — | — | WO | disclosed |