Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | S100A4 | P26447 | 2/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12849446 | 0.80 | MAPK1 (0.45) | L3MBTL1ALDH1A1TDP1S100A4PTPRC | |
| SCHEMBL1340836 | 0.78 | L3MBTL1 (0.68) | L3MBTL1HPGDALDH1A1TDP1ESR2 | |
| SCHEMBL11406237 | 0.76 | HPGD (0.68) | L3MBTL1HPGDALDH1A1TDP1ESR2 | |
| SCHEMBL1342303 | 0.74 | ALDH1A1 (0.63) | L3MBTL1HPGDALDH1A1TDP1LMNA | |
| SCHEMBL39472 | 0.72 | HPGD (0.78) | L3MBTL1HPGDALDH1A1TDP1ESR2 | |
| SCHEMBL28056476 | 0.71 | L3MBTL1 (0.81) | L3MBTL1HPGDALDH1A1TDP1ESR2 | |
| SCHEMBL3208138 | 0.70 | L3MBTL1 (0.58) | L3MBTL1HPGDALDH1A1TDP1ESR2 | |
| SCHEMBL8564440 | 0.69 | PLAUR (0.39) | L3MBTL1HPGDALDH1A1TDP1PTPRC | |
| SCHEMBL8329482 | 0.69 | L3MBTL1 (0.58) | L3MBTL1HPGDALDH1A1TDP1ESR2 | |
| SCHEMBL27952716 | 0.68 | ALDH1A1 (0.63) | L3MBTL1HPGDALDH1A1TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011034051-A1 | NOVEL CYCLIC SQUARAMIDE DERIVATIVES | 参天製薬株式会社 (JP) | 2011-03-24 | — | — | WO | disclosed |