Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 7/20 | 0.45 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | S100A4 | P26447 | 2/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12849803 | 0.80 | L3MBTL1 (0.49) | MAPK1MAPTTDP1MEN1KMT2A | |
| SCHEMBL11650656 | 0.73 | S100A4 (0.61) | MAPK1MAPTTDP1MEN1KMT2A | |
| SCHEMBL397773 | 0.72 | MAPK1 (0.77) | MAPK1MAPTTDP1MEN1KMT2A | |
| SCHEMBL2423134 | 0.70 | ALDH1A1 (0.65) | MAPK1MAPTTDP1MEN1KMT2A | |
| SCHEMBL8564440 | 0.69 | PLAUR (0.39) | MAPK1MAPTTDP1MEN1KMT2A | |
| SCHEMBL2421019 | 0.69 | MAPK1 (0.57) | MAPK1MAPTTDP1MEN1KMT2A | |
| SCHEMBL9121071 | 0.67 | MAPK1 (0.62) | MAPK1MAPTTDP1MEN1KMT2A | |
| SCHEMBL4055339 | 0.67 | MAPK1 (0.62) | MAPK1MAPTTDP1MEN1KMT2A | |
| SCHEMBL4940856 | 0.66 | L3MBTL1 (0.68) | MAPK1MAPTTDP1MEN1KMT2A | |
| SCHEMBL30819288 | 0.66 | L3MBTL1 (0.68) | MAPK1MAPTTDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011034051-A1 | NOVEL CYCLIC SQUARAMIDE DERIVATIVES | 参天製薬株式会社 (JP) | 2011-03-24 | — | — | WO | disclosed |