Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.34 |
| ▸ | PTPRC | P08575 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | FGR | P09769 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8564440 | 0.72 | PLAUR (0.39) | SMN1; SMN2SLC6A2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8564127 | 0.69 | KMT2A (0.39) | SMN1; SMN2SLC6A2ALDH1A1POLBMAPK1 | |
| SCHEMBL3943393 | 0.68 | MAPT (0.46) | SMN1; SMN2SLC6A2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1683323 | 0.67 | ADORA2A (0.65) | PDE7ASMN1; SMN2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL6366580 | 0.66 | ADORA2A (0.58) | PDE7ASMN1; SMN2SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL29869345 | 0.66 | MEN1 (0.68) | PDE7ASMN1; SMN2SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL713707 | 0.66 | MEN1 (0.68) | PDE7ASMN1; SMN2SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL10339614 | 0.65 | MAPT (0.64) | PDE7ASMN1; SMN2SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL8569652 | 0.65 | PTGS2 (0.36) | SMN1; SMN2SLC6A2ALDH1A1POLBMAPK1 | |
| SCHEMBL12849807 | 0.65 | S100A4 (0.35) | SMN1; SMN2PTPRCKMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011034051-A1 | NOVEL CYCLIC SQUARAMIDE DERIVATIVES | 参天製薬株式会社 (JP) | 2011-03-24 | — | — | WO | disclosed |