Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | CTSG | P08311 | 1/20 | 0.49 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.49 |
| ▸ | CMA1 | P23946 | 1/20 | 0.49 |
| ▸ | METAP2 | P50579 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10143994 | 1.00 | RAB9A (0.54) | RAB9AALDH1A1SMN1; SMN2NPC1MEN1 | |
| SCHEMBL12156864 | 0.87 | KMT2A (0.53) | RAB9AALDH1A1SMN1; SMN2NPC1MEN1 | |
| SCHEMBL18362239 | 0.86 | SMN1; SMN2 (0.57) | RAB9AALDH1A1SMN1; SMN2NPC1MEN1 | |
| SCHEMBL5784044 | 0.85 | SMN1; SMN2 (0.55) | RAB9AALDH1A1SMN1; SMN2NPC1MEN1 | |
| SCHEMBL820885 | 0.84 | SMN1; SMN2 (0.49) | RAB9AALDH1A1SMN1; SMN2NPC1MEN1 | |
| SCHEMBL9943346 | 0.84 | GAA (0.58) | RAB9AALDH1A1SMN1; SMN2NPC1MEN1 | |
| SCHEMBL1686722 | 0.84 | GAA (0.58) | RAB9AALDH1A1SMN1; SMN2NPC1MEN1 | |
| SCHEMBL9465072 | 0.84 | POLB (0.57) | RAB9AALDH1A1SMN1; SMN2NPC1MEN1 | |
| SCHEMBL13612866 | 0.84 | LMNA (0.57) | ALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL9464650 | 0.84 | HTT (0.59) | RAB9AALDH1A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102060801-B | Method for synthesizing 5-alkoxy-substituted oxazole compound | UNIV ZHEJIANG TECHNOLOGY | 2013-04-17 | — | — | CN | disclosed |
| CN-102060801-A | Method for synthesizing 5-alkoxy-substituted oxazole compound | UNIV ZHEJIANG TECHNOLOGY | 2011-05-18 | — | — | CN | disclosed |
| WO-2011029802-A1 | 4-SUBSTITUTED PYRIDIN-3-YL-CARBOXAMIDE COMPOUNDS AND METHODS OF USE | F. HOFFMANN-LA ROCHE AG (CH) | 2011-03-17 | — | — | WO | disclosed |