Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9464645 | 1.00 | HTT (0.59) | HTTSMN1; SMN2EPHX2TRPA1LMNA | |
| SCHEMBL12156864 | 0.87 | KMT2A (0.53) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL4652134 | 0.86 | HTT (0.61) | HTTSMN1; SMN2EPHX2TRPA1LMNA | |
| SCHEMBL27564141 | 0.85 | HTT (0.56) | HTTSMN1; SMN2TRPA1LMNAKDM4E | |
| SCHEMBL13612866 | 0.84 | LMNA (0.57) | EPHX2LMNAALDH1A1L3MBTL1MEN1 | |
| SCHEMBL10143994 | 0.84 | RAB9A (0.54) | SMN1; SMN2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL12849869 | 0.84 | RAB9A (0.54) | SMN1; SMN2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL13605093 | 0.83 | NR1H4 (0.51) | HTTSMN1; SMN2EPHX2LMNAALDH1A1 | |
| SCHEMBL2159283 | 0.82 | HPGD (0.61) | HTTSMN1; SMN2LMNAALDH1A1MEN1 | |
| SCHEMBL27995512 | 0.82 | MEN1 (0.45) | LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254548-A | Treating dysfunction of cholinergic system | ADIR ET COMPAGNIE (FR) | 1993-10-19 | — | — | US | disclosed |