Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | AKR1B10 | O60218 | 7/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 7/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1285039 | 1.00 | MAPT (0.41) | MAPTSMN1; SMN2AKR1B10AKR1B1POLB | |
| SCHEMBL1285742 | 0.92 | MAOA (0.36) | MAPTSMN1; SMN2AKR1B10AKR1B1ALDH1A1 | |
| SCHEMBL1285743 | 0.92 | MAOA (0.36) | MAPTSMN1; SMN2AKR1B10AKR1B1ALDH1A1 | |
| SCHEMBL1285076 | 0.89 | LMNA (0.38) | MAPTNPC1RAB9ATP53ALDH1A1 | |
| SCHEMBL1285073 | 0.89 | LMNA (0.38) | MAPTNPC1RAB9ATP53ALDH1A1 | |
| SCHEMBL1285421 | 0.88 | MAPT (0.44) | MAPTSMN1; SMN2POLBGPR55NPC1 | |
| SCHEMBL1285423 | 0.88 | MAPT (0.44) | MAPTSMN1; SMN2POLBGPR55NPC1 | |
| SCHEMBL1285495 | 0.88 | LMNA (0.37) | MAPTALOX5ALDH1A1LMNAHTT | |
| SCHEMBL1285494 | 0.88 | LMNA (0.37) | MAPTALOX5ALDH1A1LMNAHTT | |
| SCHEMBL1285424 | 0.88 | MAOA (0.34) | SMN1; SMN2TP53ALDH1A1HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8383843-B2 | Method for preparing a coumarin compound, chromene compound, and method for preparing a chromene compound | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2013-02-26 | — | — | US | disclosed |
| US-20120088923-A1 | METHOD FOR PREPARING A COUMARIN COMPOUND, CHROMENE COMPOUND, AND METHOD FOR PREPARING A CHROMENE COMPOUND | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2012-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088923-A1 | METHOD FOR PREPARING A COUMARIN COMPOUND, CHROMENE COMPOUND, AND METHOD FOR PREPARING A CHROMENE COMPOUND | CYP3A7, CYP2A7, F7 | MAPT 4232/4885SMN1; SMN2 4471/4885AKR1B10 118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.