SCHEMBL12852129

SCHEMBL12852129

CC1=CC(=C2C=C(C)C(=O)C(Cl)=C2)C=C(C)C1=O

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.32
USP2 O75604 2/20 0.32
ALDH1A1 P00352 2/20 0.32
GAA P10253 2/20 0.32
MAPT P10636 2/20 0.32
MAPK1 P28482 2/20 0.32
BLM P54132 2/20 0.32
KMT2A Q03164 2/20 0.32
PLIN1 O60240 1/20 0.32
NR1I2 O75469 1/20 0.32
GSR P00390 1/20 0.32
LMNA P02545 1/20 0.32
TP53 P04637 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
ADORA3 P0DMS8 1/20 0.32
CYP2D6 P10635 1/20 0.32
HSPD1 P10809 1/20 0.32
CYP2C9 P11712 1/20 0.32
PKM P14618 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12954422 0.95 MEN1 (0.32) MEN1USP2ALDH1A1GAAMAPT
SCHEMBL2741115 0.84 ALDH1A1 (0.40) MEN1USP2ALDH1A1GAAMAPT
SCHEMBL12267615 0.78 MEN1 (0.36) MEN1ALDH1A1MAPTMAPK1KMT2A
SCHEMBL5160971 0.77 MAPT (0.40) MEN1USP2ALDH1A1GAAMAPT
SCHEMBL12112011 0.70 GAA (0.56) MEN1USP2ALDH1A1GAAMAPT
SCHEMBL22473481 0.70 MEN1 (0.32) MEN1USP2ALDH1A1GAAMAPT
SCHEMBL17413869 0.70 MEN1 (0.33) MEN1USP2ALDH1A1GAAMAPT
SCHEMBL5589257 0.69 CES2 (0.40) MEN1USP2ALDH1A1GAAMAPT
SCHEMBL1274862 0.68 MAPT (0.42) MEN1USP2ALDH1A1GAAMAPT
SCHEMBL17969767 0.67 EEF2K (0.45) MEN1USP2ALDH1A1GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8278016-B2 Electrophotographic photoconductor RICOH COMPANY, LTD. (JP) 2012-10-02 US disclosed
US-8278016-B2 Electrophotographic photoconductor RICOH COMPANY, LTD. (JP) 2012-10-02 US disclosed
US-20090311616-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR RICOH COMPANY, LTD. (JP) 2009-12-17 US disclosed
US-20090311616-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR RICOH COMPANY, LTD. (JP) 2009-12-17 US disclosed