Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.33 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1274862 | 0.80 | MAPT (0.42) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL21463 | 0.80 | MAPT (0.41) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL57203 | 0.80 | MEN1 (0.50) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL12954422 | 0.77 | MEN1 (0.32) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL12852129 | 0.77 | MEN1 (0.32) | MAPTMEN1KMT2AALDH1A1HPGD | |
| Duroquinone SCHEMBL11408085 | 0.72 | DDAH1 (0.36) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL17413869 | 0.72 | MEN1 (0.33) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL13804874 | 0.70 | DDAH1 (0.37) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL9004447 | 0.68 | ALOX5 (0.52) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL28717271 | 0.68 | MEN1 (0.40) | MAPTMEN1KMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1754514-A1 | Agent and method for colouring keratin fibres | Wella Aktiengesellschaft (DE) | 2007-02-21 | — | — | EP | claimed |
| US-20070000073-A1 | Agent and method for colouring keratin fibres | PROCTER & GAMBLE COMPANY, THE | 2007-01-04 | — | — | US | claimed |
| WO-2006094217-A2 | AGENT AND METHOD FOR COLOURING KERATIN FIBRES | THE PROCTER & GAMBLE COMPANY (US) | 2006-09-08 | — | — | WO | claimed |
| US-7070625-B2 | Agent and method for coloring keratin fibers containing 2-benzothiazolinone-hydrazone and quinone derivatives | WELLA AG (DE) | 2006-07-04 | — | — | US | claimed |
| EP-1448540-A1 | AGENT AND METHOD FOR COLORING KERATIN FIBERS CONTAINING 2-BENZOTHIAZOLINONE-HYDRAZONE AND QUINONE DERIVATIVES | Wella Aktiengesellschaft (DE) | 2004-08-25 | — | — | EP | claimed |
| US-20040060124-A1 | Agent and method for coloring keratin fibers containing 2-benzothiazolinone-hydrazone and quinone derivatives | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2004-04-01 | — | — | US | claimed |
| WO-2003042199-A1 | AGENT AND METHOD FOR COLORING KERATIN FIBERS CONTAINING 2-BENZOTHIAZOLINONE-HYDRAZONE AND QUINONE DERIVATIVES | WELLA AKTIENGESELLSCHAFT (DE) | 2003-05-22 | — | — | WO | claimed |
| EP-1754514-A1 | Agent and method for colouring keratin fibres | Wella Aktiengesellschaft (DE) | 2007-02-21 | — | — | EP | disclosed |
| US-20070000073-A1 | Agent and method for colouring keratin fibres | PROCTER & GAMBLE COMPANY, THE | 2007-01-04 | — | — | US | disclosed |
| WO-2006094217-A2 | AGENT AND METHOD FOR COLOURING KERATIN FIBRES | THE PROCTER & GAMBLE COMPANY (US) | 2006-09-08 | — | — | WO | disclosed |
| US-7070625-B2 | Agent and method for coloring keratin fibers containing 2-benzothiazolinone-hydrazone and quinone derivatives | WELLA AG (DE) | 2006-07-04 | — | — | US | disclosed |
| EP-1448540-A1 | AGENT AND METHOD FOR COLORING KERATIN FIBERS CONTAINING 2-BENZOTHIAZOLINONE-HYDRAZONE AND QUINONE DERIVATIVES | Wella Aktiengesellschaft (DE) | 2004-08-25 | — | — | EP | disclosed |
| US-20040060124-A1 | Agent and method for coloring keratin fibers containing 2-benzothiazolinone-hydrazone and quinone derivatives | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2004-04-01 | — | — | US | disclosed |
| EP-0144580-B1 | TRIPHENDIOXAZINE DYES | BAYER AG (DE) | 1987-07-08 | — | — | EP | disclosed |
| EP-0222098-A2 | Water soluble triphenodioxazine compounds, process for their preparation and their use as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-05-20 | — | — | EP | disclosed |
| US-4629788-A | COLORFASTNESS; BLUE COLOR; NATURAL AND SYNTHETIC FIBER | BAYER AKTIENGESELLSCHAFT (DE) | 1986-12-16 | — | — | US | disclosed |
| US-4621138-A | Triphendioxazine dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1986-11-04 | — | — | US | disclosed |
| US-4591643-A | Triphendioxazine reactive dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1986-05-27 | — | — | US | disclosed |
| EP-0158882-A2 | Triphenedioxazine dyes | BAYER AG (DE) | 1985-10-23 | — | — | EP | disclosed |
| EP-0141996-A2 | Triphendioxazine reactive dyes | BAYER AG (DE) | 1985-05-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040060124-A1 | Agent and method for coloring keratin fibers containing 2-benzothiazolinone-hydrazone and quinone derivatives | KRT18, NDUFA1, NDUFA2 | MAPT 1723/4885MEN1 2449/4885KMT2A 540/4885 |
| US-20070000073-A1 | Agent and method for colouring keratin fibres | KRT18, CDC73, OAT | MAPT 1013/4885MEN1 3258/4885KMT2A 1376/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.