Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 2/20 | 0.56 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL276609 | 0.84 | MAPT (0.58) | NCF1MAPTKDM4ESMN1; SMN2CYP3A4 | |
| SCHEMBL29935774 | 0.76 | MAPT (0.56) | NCF1LOXL2HTR1AADRA1DADRA1A | |
| SCHEMBL333756 | 0.76 | MAPT (0.56) | NCF1LOXL2HTR1AADRA1DADRA1A | |
| SCHEMBL27917128 | 0.75 | CYP1A2 (0.60) | NCF1LOXL2HTR1AADRA1DADRA1A | |
| SCHEMBL1227713 | 0.75 | CYP1A2 (0.60) | NCF1LOXL2HTR1AADRA1DADRA1A | |
| SCHEMBL29699887 | 0.75 | CYP1A2 (0.60) | NCF1LOXL2HTR1AADRA1DADRA1A | |
| Iodide SCHEMBL10806172 | 0.73 | ALDH1A1 (0.60) | NCF1LOXL2HTR1AADRA1DADRA1A | |
| SCHEMBL134737 | 0.73 | NCF1 (0.58) | NCF1LOXL2HTR1AADRA1DADRA1A | |
| SCHEMBL30487734 | 0.73 | CYP1A2 (0.58) | NCF1LOXL2HTR1AADRA1DADRA1A | |
| SCHEMBL276512 | 0.73 | KDM4C (0.48) | MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 274 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113372334-A | 2- (4-methionyl) anilino-4-amino-5-trifluoromethylpyrimidine derivatives and application thereof | 贵州医科大学 | 2021-09-10 | — | — | CN | claimed |
| CN-106543145-B | C-Met kinases presses down agent 3- (4- fluorophenyl) pyrimidone -5- benzoic acid amides derivative, preparation method and application | 山西医科大学 | 2019-07-19 | — | — | CN | claimed |
| US-20190016745-A1 | AMINOGLYCOSIDE DERIVATIVES AND USES THEREOF IN TREATING MICROBIAL INFECTIONS | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2019-01-17 | — | — | US | claimed |
| CN-106478621-B | Quinoline or quinazoline derivative, preparation method and applications | 遵义医学院 | 2018-12-25 | — | — | CN | claimed |
| EP-3400231-A1 | AMINOGLYCOSIDE DERIVATIVES AND USES THEREOF IN TREATING MICROBIAL INFECTIONS | Technion Research & Development Foundation Limited (IL) | 2018-11-14 | — | — | EP | claimed |
| CN-108530426-A | 4- phenoxy groups substituted quinoline derivatives containing quinokysalines and its application | 沈阳药科大学 | 2018-09-14 | — | — | CN | claimed |
| EP-3344641-A1 | AMINOGLYCOSIDE DERIVATIVES AND USES THEREOF IN TREATING GENETIC DISORDERS | Eloxx Pharmaceuticals Ltd. (IL) | 2018-07-11 | — | — | EP | claimed |
| WO-2017118967-A1 | AMINOGLYCOSIDE DERIVATIVES AND USES THEREOF IN TREATING MICROBIAL INFECTIONS | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2017-07-13 | — | — | WO | claimed |
| WO-2017037719-A1 | AMINOGLYCOSIDE DERIVATIVES AND USES THEREOF IN TREATING GENETIC DISORDERS | ELOXX PHARMACEUTICALS LTD. (IL) | 2017-03-09 | — | — | WO | claimed |
| EP-1105422-B1 | HEPATITIS C INHIBITOR PEPTIDES | BOEHRINGER INGELHEIM CA LTD (CA) | 2006-02-15 | — | — | EP | claimed |
| EP-1105422-A1 | HEPATITIS C INHIBITOR PEPTIDES | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2001-06-13 | — | — | EP | claimed |
| WO-2000009558-A1 | HEPATITIS C INHIBITOR PEPTIDES | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2000-02-24 | — | — | WO | claimed |
| EP-0973767-A1 | INDAZOLES OF CYCLIC UREAS USEFUL AS HIV PROTEASE INHIBITORS | Dupont Pharmaceuticals Company (US) | 2000-01-26 | — | — | EP | claimed |
| WO-1998043969-A1 | INDAZOLES OF CYCLIC UREAS USEFUL AS HIV PROTEASE INHIBITORS | DUPONT PHARMACEUTICALS COMPANY (US) | 1998-10-08 | — | — | WO | claimed |
| EP-0436199-B1 | Cyclopropyl derivative lipoxygenase inhibitors | ABBOTT LAB (US) | 1994-08-03 | — | — | EP | claimed |
| US-5294716-A | Chemical process for making angiotesin II antagonist compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-03-15 | — | — | US | claimed |
| US-5245035-A | HETEROCYCLIC BORON COMPOUNDS AS INTERMEDIATES FOR ANGIOTENSIN II ANTAGONISTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-09-14 | — | — | US | claimed |
| EP-0495626-A1 | Process for the preparation of tetrazole derivatives | ZENECA LIMITED (GB) | 1992-07-22 | — | — | EP | claimed |
| EP-0495627-A1 | Boron compounds | ZENECA LIMITED (GB) | 1992-07-22 | — | — | EP | claimed |
| EP-0436199-A1 | Cyclopropyl derivative lipoxygenase inhibitors | ABBOTT LABORATORIES (US) | 1991-07-10 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190016745-A1 | AMINOGLYCOSIDE DERIVATIVES AND USES THEREOF IN TREATING MICROBIAL INFECTIONS | ALPI, MGAM, AASDHPPT | NCF1 3673/4885LOXL2 3871/4885HTR1A 4108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.