Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 5/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1285256 | 0.84 | EPHX2 (0.30) | EPHX2 | |
| SCHEMBL19638262 | 0.69 | CYP3A4 (0.36) | CHRM2CHRM1MEN1KMT2ACYP2D6 | |
| SCHEMBL1285655 | 0.69 | — | — | |
| SCHEMBL27439117 | 0.65 | CHRM2 (0.38) | CHRM2CHRM1MEN1KMT2ACYP2D6 | |
| SCHEMBL2172992 | 0.64 | CHRM2 (0.39) | CHRM2CHRM1MEN1KMT2ACYP2D6 | |
| SCHEMBL7675335 | 0.64 | CHRM2 (0.35) | CHRM2CHRM1MEN1KMT2ACYP2D6 | |
| SCHEMBL24059815 | 0.63 | SLC6A12 (0.38) | MEN1KMT2ACYP2D6EPHX2ALOX15 | |
| SCHEMBL16534886 | 0.63 | — | — | |
| SCHEMBL11870986 | 0.62 | CHRM2 (0.34) | CHRM2CHRM1MEN1KMT2ACYP2D6 | |
| SCHEMBL20142222 | 0.62 | CHRM2 (0.42) | CHRM2CHRM1MEN1KMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8357357-B2 | 3.2.1-bicyclo-octene and -octane compounds | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2013-01-22 | — | — | US | claimed |
| US-20120087884-A1 | NOVEL 3.2.1-BICYCLO-OCTENE AND -OCTANE COMPOUNDS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2012-04-12 | — | — | US | claimed |
| US-20120087886-A1 | NOVEL 3.2.1-BICYCLO-OCTENE AND -OCTANE COMPOUNDS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2012-04-12 | — | — | US | claimed |
| US-8071529-B1 | 3.2.1-bicyclo-octene and -octane compounds | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2011-12-06 | — | — | US | claimed |
| US-8415391-B2 | 3.2.1-bicyclo-octene and -octane compounds | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2013-04-09 | — | — | US | disclosed |
| US-8415391-B2 | 3.2.1-bicyclo-octene and -octane compounds | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2013-04-09 | — | — | US | disclosed |
| US-8415391-B2 | 3.2.1-bicyclo-octene and -octane compounds | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2013-04-09 | — | — | US | disclosed |
| US-8357357-B2 | 3.2.1-bicyclo-octene and -octane compounds | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2013-01-22 | — | — | US | disclosed |
| US-8357357-B2 | 3.2.1-bicyclo-octene and -octane compounds | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2013-01-22 | — | — | US | disclosed |
| US-8357357-B2 | 3.2.1-bicyclo-octene and -octane compounds | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2013-01-22 | — | — | US | disclosed |
| US-20120087884-A1 | NOVEL 3.2.1-BICYCLO-OCTENE AND -OCTANE COMPOUNDS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2012-04-12 | — | — | US | disclosed |
| US-20120087886-A1 | NOVEL 3.2.1-BICYCLO-OCTENE AND -OCTANE COMPOUNDS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2012-04-12 | — | — | US | disclosed |
| US-20120087886-A1 | NOVEL 3.2.1-BICYCLO-OCTENE AND -OCTANE COMPOUNDS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2012-04-12 | — | — | US | disclosed |
| US-20120087884-A1 | NOVEL 3.2.1-BICYCLO-OCTENE AND -OCTANE COMPOUNDS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2012-04-12 | — | — | US | disclosed |
| US-20120087886-A1 | NOVEL 3.2.1-BICYCLO-OCTENE AND -OCTANE COMPOUNDS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2012-04-12 | — | — | US | disclosed |
| US-20120087884-A1 | NOVEL 3.2.1-BICYCLO-OCTENE AND -OCTANE COMPOUNDS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2012-04-12 | — | — | US | disclosed |
| US-8071529-B1 | 3.2.1-bicyclo-octene and -octane compounds | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2011-12-06 | — | — | US | disclosed |
| US-8071529-B1 | 3.2.1-bicyclo-octene and -octane compounds | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2011-12-06 | — | — | US | disclosed |
| US-8071529-B1 | 3.2.1-bicyclo-octene and -octane compounds | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2011-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120087884-A1 | NOVEL 3.2.1-BICYCLO-OCTENE AND -OCTANE COMPOUNDS | TRPA1, TRPV1, CYP51A1 | CHRM2 3144/4885CHRM1 2536/4885MEN1 2909/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.