Biphenyl

Biphenyl

SCHEMBL128558

P.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.90

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.90
MAPK1 P28482 2/20 0.56
TAAR1 Q96RJ0 2/20 0.56
CYP1A2 P05177 1/20 0.56
CYP3A4 P08684 1/20 0.56
HSD17B10 Q99714 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
NOTUM Q6P988 1/20 0.56
MMP3 P08254 1/20 0.56
BCL2L1 Q07817 1/20 0.56
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
ATM Q13315 1/20 0.50
SLC22A2 O15244 1/20 0.50
SLC22A1 O15245 1/20 0.50
SLC22A3 O75751 1/20 0.50
SLC6A4 P31645 1/20 0.50
MAOA P21397 1/20 0.47
NFKB1 P19838 1/20 0.47
NFKB2 Q00653 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL3694239 1.00 ALDH1A1 (0.90) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
Biphenyl SCHEMBL9579759 1.00 ALDH1A1 (0.90) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
Biphenyl SCHEMBL11354282 1.00 ALDH1A1 (0.90) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
Phosphine SCHEMBL29048968 0.95 ALDH1A1 (0.82) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
Biphenyl SCHEMBL7101084 0.95 ALDH1A1 (0.82) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
Biphenyl SCHEMBL593675 0.95 ALDH1A1 (0.82) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
Biphenyl SCHEMBL7865199 0.95 ALDH1A1 (0.82) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
Biphenyl SCHEMBL9655478 0.95 ALDH1A1 (0.82) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
Biphenyl SCHEMBL28814327 0.95 ALDH1A1 (0.82) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
Biphenyl SCHEMBL10730305 0.95 ALDH1A1 (0.82) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3808 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122059993-A Preparation method and application of cuprous iodide cluster material based on diphenylphosphine quinoline ligand 黑龙江大学 2026-05-19 CN claimed
CN-122037532-A Moisture-heat-resistant flame-retardant polyurethane and host-guest chemical preparation method thereof 浙江桐轩医疗科技有限公司 2026-05-15 CN claimed
US-12577236-B2 Processes for preparation of Tezacaftor LAURUS LABS LIMITED (IN) 2026-03-17 US claimed
US-12344586-B2 Process for the preparation of biphenylamines ADAMA MAKHTESHIM LTD. (IL) 2025-07-01 US claimed
CN-120192341-A Dithiophosphonate ester method for synthesizing compound 信阳师范大学 2025-06-24 CN claimed
CN-120157837-A Polyurethane primer resin synthesis process 海南睿霖盛欣科技有限公司 2025-06-17 CN claimed
CN-120138828-A Colored polyethylene fiber and preparation method thereof 比音勒芬服饰股份有限公司 2025-06-13 CN claimed
CN-120152789-A Heterogeneous catalyst 陶氏环球技术有限责任公司 2025-06-13 CN claimed
CN-120079262-A Novel filtering membrane for VB12 production process and preparation method thereof 宁夏沃滴滴水肥科技有限公司 2025-06-03 CN claimed
CN-119708799-B Cured product of organic phosphine modified unsaturated polyester and polyhalide and preparation method thereof 浙江工业大学 2025-05-30 CN claimed
EP-0478009-A2 Polycondensation catalyst SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1992-04-01 EP claimed
EP-0292629-A2 Polycondensation catalyst SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1988-11-30 EP claimed
US-4778873-A MIXTURE OF PHOSPHORUS-SILICON COMPOUND AND ACID ACCEPTOR THE GOODYEAR TIRE & RUBBER COMPANY (US) 1988-10-18 US claimed
CN-87107325-A Selective preparation of alkene carboxylic acid derivatives 1988-06-22 CN claimed
US-4668762-A OXYGEN-SILICON-PHOSPHORUS-CONTAINING COMPOUNDS, ACID ACCEPTORS AND HALO COMPOUND TO MAKE POLYESTERS,-UREAS AND AMIDES AT LOW TEMPERATURE THE GOODYEAR TIRE & RUBBER COMPANY (US) 1987-05-26 US claimed
EP-0032455-B1 IMPROVED HETEROGENEOUS CATALYST UNISEARCH LIMITED (AU) 1984-04-18 EP claimed
US-4432889-A GRAFTING STYRYL-(OR PHENYL ACRYLYL-)DIPHENYL PHOSPHINE ONTO SUBSTRATE, THEN REACTING WITH CATALYST UNISEARCH LIMITED (AU) 1984-02-21 US claimed
US-4386013-A COMPOSITE OF RHODIUM METAL OR COMPOUND AND A TETRAVALENT COORDINATING COMPOUND OCCIDENTAL RESEARCH CORPORATION (US) 1983-05-31 US claimed
EP-0032455-A2 Improved heterogeneous catalyst UNISEARCH LIMITED (AU) 1981-07-22 EP claimed
US-4027084-A FROM DIPHOSPHINE ALKALI ALCOHOLATES AND A HALOGENATED POLYMER SOCIETE NATIONALE DES PETROLES D'AQUITAINE (FR) 1977-05-31 US claimed