Biphenyl

Biphenyl

SCHEMBL7101084

P.P.[Ni].c1ccc(-c2ccccc2)cc1

nearest known ligand 0.82

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.82
MAPK1 P28482 2/20 0.53
TAAR1 Q96RJ0 2/20 0.53
CYP1A2 P05177 1/20 0.53
CYP3A4 P08684 1/20 0.53
HSD17B10 Q99714 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
NOTUM Q6P988 1/20 0.53
MMP3 P08254 1/20 0.53
BCL2L1 Q07817 1/20 0.53
ATM Q13315 1/20 0.47
SLC22A2 O15244 1/20 0.47
SLC22A1 O15245 1/20 0.47
SLC22A3 O75751 1/20 0.47
SLC6A4 P31645 1/20 0.47
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
MAOA P21397 1/20 0.45
NFKB1 P19838 1/20 0.45
NFKB2 Q00653 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL10530692 0.95 ALDH1A1 (0.90) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
Biphenyl SCHEMBL31498550 0.95 ALDH1A1 (0.90) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
Biphenyl SCHEMBL3694239 0.95 ALDH1A1 (0.90) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
Biphenyl SCHEMBL128558 0.95 ALDH1A1 (0.90) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
Biphenyl SCHEMBL11354282 0.95 ALDH1A1 (0.90) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
Biphenyl SCHEMBL9579759 0.95 ALDH1A1 (0.90) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
Biphenyl SCHEMBL7865199 0.91 ALDH1A1 (0.82) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
Biphenyl SCHEMBL9655478 0.91 ALDH1A1 (0.82) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
Biphenyl SCHEMBL593675 0.91 ALDH1A1 (0.82) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
Phosphine SCHEMBL29048968 0.91 ALDH1A1 (0.82) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0988330-B1 METHOD FOR THE PREPARATION OF COPOLYMERS OF ETHYLENE/NORBORNENE-TYPE MONOMERS WITH NICKEL CATALYSTS SUMITOMO BAKELITE CO (JP) 2003-09-03 EP claimed
EP-0988330-A1 METHOD FOR THE PREPARATION OF COPOLYMERS OF ETHYLENE/NORBORNENE-TYPE MONOMERS WITH NICKEL CATALYSTS THE B.F. GOODRICH COMPANY (US) 2000-03-29 EP claimed
US-5929181-A Method for preparation of copolymers of ethylene/norbornene-type monomers with nickel catalysts THE B.F.GOODRICH CO. (US) 1999-07-27 US claimed
WO-1998056837-A1 METHOD FOR THE PREPARATION OF COPOLYMERS OF ETHYLENE/NORBORNENE-TYPE MONOMERS WITH NICKEL CATALYSTS THE B.F. GOODRICH COMPANY (US) 1998-12-17 WO claimed