Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.76 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | ACHE | P22303 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | MPO | P05164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL23850614 | 0.96 | LMNA (0.71) | KMT2ACYP2A13LMNAACHEKDM4E | |
| SCHEMBL329437 | 0.94 | KMT2A (0.72) | KMT2ACYP2A13LMNAACHEKDM4E | |
| SCHEMBL1882777 | 0.92 | KMT2A (0.70) | KMT2ACYP2A13LMNAACHEKDM4E | |
| SCHEMBL1164984 | 0.92 | KMT2A (0.70) | KMT2ACYP2A13LMNAACHEKDM4E | |
| SCHEMBL30341035 | 0.89 | KMT2A (0.66) | KMT2ACYP2A13LMNAACHEKDM4E | |
| SCHEMBL11891934 | 0.86 | KMT2A (0.73) | KMT2ACYP2A13LMNAACHEKDM4E | |
| SCHEMBL24403536 | 0.86 | KMT2A (1.00) | KMT2ACYP2A13LMNAACHEKDM4E | |
| SCHEMBL12864587 | 0.84 | KMT2A (0.56) | KMT2ACYP2A13LMNAACHEKDM4E | |
| SCHEMBL14818737 | 0.83 | LMNA (0.84) | KMT2ACYP2A13LMNAACHEKDM4E | |
| SCHEMBL29863134 | 0.83 | LMNA (0.84) | KMT2ACYP2A13LMNAACHEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7884097-B2 | Contains 1-(2-Aminoethyl)piperidine and 2-adamantanone; mycobacterial infections | SEQUELLA, INC. (US) | 2011-02-08 | — | — | US | disclosed |