SCHEMBL329437

SCHEMBL329437

Cc1ccccc1CN1CCCC1

nearest known ligand 0.72

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.72
CYP2A13 Q16696 1/20 0.70
LMNA P02545 2/20 0.68
ACHE P22303 1/20 0.68
KDM4E B2RXH2 5/20 0.58
ALDH1A1 P00352 6/20 0.58
MEN1 O00255 3/20 0.53
TDP1 Q9NUW8 2/20 0.53
GAA P10253 1/20 0.53
ATM Q13315 1/20 0.53
NPSR1 Q6W5P4 1/20 0.53
CHRNA7 P36544 1/20 0.51
MAPT P10636 1/20 0.51
CYP2C19 P33261 1/20 0.51
SMN1; SMN2 Q16637 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1164984 0.98 KMT2A (0.70) KMT2ACYP2A13LMNAACHEKDM4E
SCHEMBL1882777 0.98 KMT2A (0.70) KMT2ACYP2A13LMNAACHEKDM4E
SCHEMBL12856255 0.94 KMT2A (0.76) KMT2ACYP2A13LMNAACHEKDM4E
Hydrochloric Acid SCHEMBL23850614 0.94 LMNA (0.71) KMT2ACYP2A13LMNAACHEKDM4E
SCHEMBL30341035 0.90 KMT2A (0.66) KMT2ACYP2A13LMNAACHEKDM4E
SCHEMBL3930857 0.87 LMNA (0.60) KMT2ACYP2A13LMNAACHEKDM4E
SCHEMBL6791318 0.85 HTR7 (0.59) KMT2ACYP2A13LMNAACHEKDM4E
SCHEMBL14818737 0.84 LMNA (0.84) KMT2ACYP2A13LMNAACHEKDM4E
SCHEMBL29863134 0.84 LMNA (0.84) KMT2ACYP2A13LMNAACHEKDM4E
SCHEMBL11196594 0.84 ALDH1A1 (0.69) KMT2ALMNAKDM4EALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer ANIMA BIOTECH INC. (US) 2025-07-01 US disclosed
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2025-04-03 US disclosed
WO-2022135590-A1 PYRIMIDO-HETEROCYCLIC COMPOUNDS, AND PREPARATION METHOD THEREFOR AND USE THEREOF 上海凌达生物医药有限公司 2022-06-30 WO disclosed
US-10179124-B2 Benzamides and related inhibitors of factor Xa MILLENNIUM PHARMACEUTICALS, INC. (US) 2019-01-15 US disclosed
EP-3169662-B1 SUBSTITUTED VINYL- AND ALKINYL-CYANOCYCLOALKANOLS AND VINYL- AND ALKINYL-CYANOHETEROCYCLOALKANOLS AS AGENTS TO COMBAT ABIOTIC PLANT STRESS BAYER CROPSCIENCE AG (DE) 2018-07-11 EP disclosed
US-20180036296-A1 BENZAMIDES AND RELATED INHIBITORS OF FACTOR XA COR THERAPEUTICS, INC. 2018-02-08 US disclosed
US-20180036296-A1 BENZAMIDES AND RELATED INHIBITORS OF FACTOR XA COR THERAPEUTICS, INC. 2018-02-08 US disclosed
CN-107567445-A It can be used as 2 phenyl 3H imidazos [4,5 B] pyridine derivates of mammal EGFR-TK ROR1 activities inhibitor 坎塞拉有限公司 2018-01-09 CN disclosed
US-9629831-B2 Benzamides and related inhibitors of factor XA MILLENNIUM PHARMACEUTICALS, INC. (US) 2017-04-25 US disclosed
US-9629831-B2 Benzamides and related inhibitors of factor XA MILLENNIUM PHARMACEUTICALS, INC. (US) 2017-04-25 US disclosed
US-20040254301-A1 Conjugated diolefin (co)polymer rubber, process for producing (co)polymer rubber, rubber composition, composite, and tire JSR CORPORATION (JP) 2004-12-16 US disclosed
EP-1457501-A1 CONJUGATED DIOLEFIN POLYMER RUBBER PROCESS FOR PRODUCING POLYMER RUBBER RUBBER COMPOSITION COMPOSITE AND TIRE JSR Corporation (JP) 2004-09-15 EP disclosed
US-20040116399-A1 Inhibitors of factor Xa MILLENNIUM PHARMACEUTICALS, INC. 2004-06-17 US disclosed
US-20040116399-A1 Inhibitors of factor Xa MILLENNIUM PHARMACEUTICALS, INC. 2004-06-17 US disclosed
EP-0924227-B1 Conjugated diolefin-based copolymer rubber and composition thereof JSR CORP (JP) 2004-03-10 EP disclosed
US-20030125448-A1 A butadiene-styrene copolymer having end terminals modified with a tin compound and amino compound; molecular weight distribution, tire rolling resistance, hysteresis-free, wear resistance GOODYEAR TIRE & RUBBER COMPANY, THE 2003-07-03 US disclosed
EP-1318172-A1 Pneumatic tire having a rubber component containing a tin/amino functionalized rubber and an inversion carbon black THE GOODYEAR TIRE & RUBBER COMPANY (US) 2003-06-11 EP disclosed
US-6191234-B1 CONJUGATED DIENE-AROMATIC VINYL COPOLYMER OBTAINED BY MODIFYING POLYMER WITH A AMINO GROUP IS USED TO IMPROVE WET SKID RESISTANCE, WEAR RESISTANCE OF AUTOMOBILE TIRE TREAD JSR CORPORATION (JP) 2001-02-20 US disclosed
EP-0924227-A1 Conjugated diolefin-based copolymer rubber and composition thereof JSR Corporation (JP) 1999-06-23 EP disclosed
WO-1999011648-A1 ORGANOMETALLIC COMPOUNDS, THEIR PREPARATION AND USE ZENECA LIMITED (GB) 1999-03-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180036296-A1 BENZAMIDES AND RELATED INHIBITORS OF FACTOR XA TFPI, F12, TFPI2 KMT2A 1317/4885CYP2A13 792/4885LMNA 218/4885
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer MYC, MYCBP, MYCBP2 KMT2A 1404/4885CYP2A13 4649/4885LMNA 1344/4885
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER MYC, MYCBP, MYCBP2 KMT2A 1404/4885CYP2A13 4649/4885LMNA 1344/4885
US-10179124-B2 Benzamides and related inhibitors of factor Xa TFPI, F12, TFPI2 KMT2A 1317/4885CYP2A13 792/4885LMNA 218/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.