Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1762432 | 0.89 | CYP17A1 (0.34) | DHODHCYP17A1CYP1A2ALDH1A1POLB | |
| SCHEMBL950938 | 0.89 | CYP17A1 (0.34) | DHODHCYP17A1CYP1A2ALDH1A1POLB | |
| SCHEMBL25008237 | 0.87 | OPRL1 (0.34) | DHODHCYP17A1CYP1A2ALDH1A1POLB | |
| SCHEMBL31060065 | 0.87 | DHODH (0.33) | DHODHCYP17A1CYP1A2ALDH1A1POLB | |
| SCHEMBL950829 | 0.87 | DHODH (0.35) | DHODHCYP17A1CYP1A2ALDH1A1POLB | |
| SCHEMBL29598524 | 0.87 | DHODH (0.43) | DHODHCYP17A1CYP1A2ALDH1A1POLB | |
| SCHEMBL465839 | 0.87 | DHODH (0.43) | DHODHCYP17A1CYP1A2ALDH1A1POLB | |
| SCHEMBL12529033 | 0.86 | DHODH (0.32) | DHODHCYP17A1CYP1A2ALDH1A1POLB | |
| SCHEMBL950557 | 0.86 | DHODH (0.33) | DHODHCYP17A1CYP1A2ALDH1A1POLB | |
| SCHEMBL951779 | 0.85 | ALDH1A1 (0.33) | DHODHCYP17A1CYP1A2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2281810-A1 | AMIDE COMPOUNDS, PREPARATION METHODS AND USES THEREOF | Sinochem Corporation (CN) | 2011-02-09 | — | — | EP | disclosed |