Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 2/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KLK7 | P49862 | 1/20 | 0.31 |
| ▸ | KLK14 | Q9P0G3 | 1/20 | 0.31 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 2/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.30 |
| ▸ | CDK4 | P11802 | 1/20 | 0.30 |
| ▸ | CCND1 | P24385 | 1/20 | 0.30 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31060065 | 0.93 | DHODH (0.33) | DHODHCYP17A1CYP1A2MAPTNPSR1 | |
| SCHEMBL12529033 | 0.92 | DHODH (0.32) | DHODHCYP17A1CYP1A2MAPTNPSR1 | |
| SCHEMBL30233941 | 0.90 | DHODH (0.32) | DHODHCYP17A1CYP1A2MAPTNPSR1 | |
| SCHEMBL25008724 | 0.90 | SLC16A3 (0.34) | DHODHCYP17A1CYP1A2MAPTNPSR1 | |
| SCHEMBL29215191 | 0.90 | DHODH (0.32) | DHODHCYP17A1CYP1A2MAPTNPSR1 | |
| SCHEMBL25008097 | 0.90 | PTGS2 (0.32) | DHODHCYP17A1CYP1A2MAPTNPSR1 | |
| SCHEMBL950938 | 0.89 | CYP17A1 (0.34) | DHODHCYP17A1CYP1A2MAPTNPSR1 | |
| SCHEMBL1762432 | 0.89 | CYP17A1 (0.34) | DHODHCYP17A1CYP1A2MAPTNPSR1 | |
| SCHEMBL12856449 | 0.87 | DHODH (0.33) | DHODHCYP17A1CYP1A2MAPTNPSR1 | |
| SCHEMBL465839 | 0.87 | DHODH (0.43) | DHODHCYP17A1CYP1A2MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240308988-A1 | Method For Controlling Diamide Resistant Pests and Compounds Therefor | SYNGENTA CROP PROTECTION AG (CH) | 2024-09-19 | — | — | US | disclosed |
| EP-4380363-A1 | METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR | Syngenta Crop Protection AG (CH) | 2024-06-12 | — | — | EP | disclosed |
| CN-118076228-A | Methods for controlling diamide-resistant pests and compounds thereof | 先正达农作物保护股份公司 | 2024-05-24 | — | — | CN | disclosed |
| WO-2023012081-A1 | METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR | SYNGENTA CROP PROTECTION AG (CH) | 2023-02-09 | — | — | WO | disclosed |
| WO-2023012081-A1 | METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR | SYNGENTA CROP PROTECTION AG (CH) | 2023-02-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240308988-A1 | Method For Controlling Diamide Resistant Pests and Compounds Therefor | DDT, NOS1, SLC11A2 | OPRL1 3514/4885DHODH 90/4885CYP17A1 872/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.