SCHEMBL12856552

SCHEMBL12856552

O=C1c2cc(-c3ccccc3-c3ccccc3)ccc2-c2ccc(-c3ccccc3-c3ccccc3)cc21

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.64
RAB9A P51151 4/20 0.64
SMN1; SMN2 Q16637 4/20 0.64
MEN1 O00255 4/20 0.64
KMT2A Q03164 4/20 0.64
APAF1 O14727 3/20 0.64
LMNA P02545 3/20 0.64
HTT P42858 3/20 0.64
GALK1 P51570 3/20 0.64
BLM P54132 3/20 0.64
NPSR1 Q6W5P4 3/20 0.64
PTBP1 P26599 2/20 0.64
SMAD3 P84022 2/20 0.64
MAPT P10636 2/20 0.64
THRB P10828 2/20 0.64
XBP1 P17861 1/20 0.64
ATM Q13315 1/20 0.64
L3MBTL1 Q9Y468 1/20 0.64
PTPRC P08575 10/20 0.58
PTPN1 P18031 3/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19001704 0.98 NPC1 (0.68) NPC1RAB9ASMN1; SMN2MEN1KMT2A
SCHEMBL3925146 0.96 NPC1 (0.64) NPC1RAB9ASMN1; SMN2MEN1KMT2A
SCHEMBL19001851 0.94 NPC1 (0.74) NPC1RAB9ASMN1; SMN2MEN1KMT2A
SCHEMBL1482692 0.87 MEN1 (0.84) NPC1RAB9ASMN1; SMN2MEN1KMT2A
SCHEMBL7322266 0.87 MEN1 (0.84) NPC1RAB9ASMN1; SMN2MEN1KMT2A
SCHEMBL15943462 0.87 NPC1 (0.55) NPC1RAB9ASMN1; SMN2MEN1KMT2A
SCHEMBL2350060 0.86 NPC1 (0.76) NPC1RAB9ASMN1; SMN2MEN1KMT2A
SCHEMBL1480040 0.86 NPC1 (0.76) NPC1RAB9ASMN1; SMN2MEN1KMT2A
SCHEMBL30481072 0.86 NPC1 (0.76) NPC1RAB9ASMN1; SMN2MEN1KMT2A
SCHEMBL21993324 0.84 NPC1 (0.80) NPC1RAB9ASMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2791275-B1 ORGANIC SENSITIZERS FOR UP-CONVERSION MERCK PATENT GMBH (DE) 2017-05-31 EP disclosed
US-20140358198-A1 ORGANIC SENSITIZERS FOR UP-CONVERSION MERCK PATENT GMBH (DE) 2014-12-04 US disclosed
US-20140358198-A1 ORGANIC SENSITIZERS FOR UP-CONVERSION MERCK PATENT GMBH (DE) 2014-12-04 US disclosed
WO-2013087162-A1 ORGANIC SENSITIZERS FOR UP-CONVERSION MERCK PATENT GMBH (DE) 2013-06-20 WO disclosed
EP-2281861-A2 Mixture of organic emission-enabled semiconductors and matrix materials, use of same and electronic components containing same Merck Patent GmbH (DE) 2011-02-09 EP disclosed
US-7345301-B2 Mixtures of matrix materials and organic semiconductors capable of emission, use of the same and electronic components containing said mixtures MERCK PATENT GMBH (DE) 2008-03-18 US disclosed
US-7345301-B2 Mixtures of matrix materials and organic semiconductors capable of emission, use of the same and electronic components containing said mixtures MERCK PATENT GMBH (DE) 2008-03-18 US disclosed