SCHEMBL21993324

SCHEMBL21993324

O=C1c2ccccc2C(=O)c2cc(-c3ccc(-c4ccccc4)cc3)ccc21

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 5/20 0.80
RAB9A P51151 5/20 0.80
SMN1; SMN2 Q16637 4/20 0.80
MAPT P10636 3/20 0.80
L3MBTL1 Q9Y468 3/20 0.80
MEN1 O00255 2/20 0.80
KMT2A Q03164 2/20 0.80
LMNA P02545 2/20 0.80
APAF1 O14727 1/20 0.80
THRB P10828 1/20 0.80
XBP1 P17861 1/20 0.80
PTBP1 P26599 1/20 0.80
HTT P42858 1/20 0.80
GALK1 P51570 1/20 0.80
BLM P54132 1/20 0.80
SMAD3 P84022 1/20 0.80
ATM Q13315 1/20 0.80
NPSR1 Q6W5P4 1/20 0.80
PTPRC P08575 6/20 0.55
PTPN1 P18031 3/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30722379 1.00 NPC1 (0.80) NPC1RAB9ASMN1; SMN2MAPTL3MBTL1
SCHEMBL57813 1.00 NPC1 (0.80) NPC1RAB9ASMN1; SMN2MAPTL3MBTL1
SCHEMBL7322266 0.98 MEN1 (0.84) NPC1RAB9ASMN1; SMN2MAPTL3MBTL1
SCHEMBL1482692 0.98 MEN1 (0.84) NPC1RAB9ASMN1; SMN2MAPTL3MBTL1
SCHEMBL4410719 0.98 MEN1 (0.76) NPC1RAB9ASMN1; SMN2MAPTL3MBTL1
SCHEMBL19001850 0.94 NPC1 (0.78) NPC1RAB9ASMN1; SMN2MAPTL3MBTL1
SCHEMBL19001853 0.94 NPC1 (0.78) NPC1RAB9ASMN1; SMN2MAPTL3MBTL1
SCHEMBL28198235 0.93 MEN1 (0.92) NPC1RAB9ASMN1; SMN2MAPTL3MBTL1
SCHEMBL978978 0.93 NPC1 (0.92) NPC1RAB9ASMN1; SMN2MAPTL3MBTL1
SCHEMBL18073335 0.93 NPC1 (0.83) NPC1RAB9ASMN1; SMN2MAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200148538-A1 SURFACE-MODIFIED INORGANIC NITRIDE, COMPOSITION, THERMALLY CONDUCTIVE MATERIAL, AND DEVICE WITH THERMALLY CONDUCTIVE LAYER FUJIFILM CORPORATION (JP) 2020-05-14 US disclosed
CN-101263097-B Method for producing aromatic compound and aromatic compound obtained by the method IDEMITSU KOSAN CO 2013-05-01 CN disclosed
CN-101263097-A Method for producing aromatic compound and aromatic compound obtained by the method IDEMITSU KOSAN CO (JP) 2008-09-10 CN disclosed