Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.62 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | BLM | P54132 | 3/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9102046 | 0.81 | PPARG (0.69) | PPARGADORA3ALDH1A1LMNATSHR | |
| SCHEMBL28407544 | 0.80 | ATM (0.76) | PPARGADORA3ALDH1A1LMNATSHR | |
| SCHEMBL11881278 | 0.80 | PPARG (0.67) | PPARGADORA3ALDH1A1LMNATSHR | |
| SCHEMBL13847974 | 0.79 | PPARG (0.64) | PPARGADORA3ALDH1A1LMNATSHR | |
| SCHEMBL28407181 | 0.78 | PPARG (0.76) | PPARGADORA3ALDH1A1LMNATSHR | |
| SCHEMBL28905340 | 0.77 | PPARG (0.64) | PPARGADORA3ALDH1A1LMNATSHR | |
| SCHEMBL27513111 | 0.76 | PPARG (1.00) | PPARGADORA3ALDH1A1LMNATSHR | |
| SCHEMBL11874263 | 0.76 | PPARG (0.69) | PPARGADORA3ALDH1A1LMNATSHR | |
| SCHEMBL24162709 | 0.76 | PPARG (0.65) | PPARGADORA3ALDH1A1LMNATSHR | |
| SCHEMBL12869021 | 0.75 | PPARG (0.67) | PPARGADORA3ALDH1A1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110040057-A1 | LIGAND-COUPLED INITIATOR POLYMERS AND METHODS OF USE | Surmodics Coatings, LLC | 2011-02-17 | — | — | US | disclosed |
| US-20110040057-A1 | LIGAND-COUPLED INITIATOR POLYMERS AND METHODS OF USE | Surmodics Coatings, LLC | 2011-02-17 | — | — | US | disclosed |
| US-7820158-B2 | Ligand-coupled initiator polymers and methods of use | SURMODICS, INC. (US) | 2010-10-26 | — | — | US | disclosed |
| US-7820158-B2 | Ligand-coupled initiator polymers and methods of use | SURMODICS, INC. (US) | 2010-10-26 | — | — | US | disclosed |
| EP-1613749-B1 | LIGAND-COUPLED INITIATOR POLYMERS AND METHODS OF USE | SURMODICS INC (US) | 2010-07-07 | — | — | EP | disclosed |