Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | RXRA | P19793 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 3/20 | 0.34 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.34 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12858074 | 0.94 | ACHE (0.46) | ACHERXRAOPRM1OPRL1KCNA5 | |
| SCHEMBL12857832 | 0.91 | ACHE (0.52) | ACHERXRAOPRM1OPRL1KCNA5 | |
| SCHEMBL12857751 | 0.91 | ACHE (0.52) | ACHERXRAOPRM1OPRL1KCNA5 | |
| SCHEMBL12857684 | 0.87 | ACHE (0.47) | ACHERXRAKCNA5RELAKDM4E | |
| SCHEMBL12857728 | 0.87 | ACHE (0.47) | ACHERXRAKCNA5RELAKDM4E | |
| SCHEMBL12857741 | 0.87 | ACHE (0.47) | ACHERXRAKCNA5RELAKDM4E | |
| SCHEMBL12857809 | 0.85 | OPRM1 (0.49) | RXRAOPRM1OPRL1KDM4EBACE1 | |
| SCHEMBL12857816 | 0.85 | ACHE (0.56) | ACHERXRAOPRM1OPRL1KCNA5 | |
| SCHEMBL12857675 | 0.85 | ACHE (0.56) | ACHERXRAOPRM1OPRL1KCNA5 | |
| SCHEMBL12858076 | 0.83 | ACHE (0.43) | ACHERXRAKCNA5RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9963563-B2 | Reversible derivatization of poly (aryl ether ketones) | CYTEC TECHNOLOGY CORP. (US) | 2018-05-08 | — | — | US | disclosed |
| US-20180030227-A1 | REVERSIBLE DERIVATIZATION OF POLY (ARYL ETHER KETONES) | CYTEC TECHNOLOGY CORP. (US) | 2018-02-01 | — | — | US | disclosed |
| US-9828478-B2 | Reversible derivatization of poly (aryl ether ketones) | CYTEC TECHNOLOGY CORP. (US) | 2017-11-28 | — | — | US | disclosed |
| US-20160075840-A1 | Reversible Derivatization of Poly (Aryl Ether Ketones) | CYTEC TECHNOLOGY CORP. (US) | 2016-03-17 | — | — | US | disclosed |
| US-20110040045-A1 | REVERSIBLE DERIVATIZATION OF POLY (ARYL ETHER KETONES) | CYTEC TECHNOLOGY CORP. | 2011-02-17 | — | — | US | disclosed |