Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.52 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.50 |
| ▸ | HTR7 | P34969 | 5/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL525069 | 1.00 | PAOX (0.52) | PAOXTBXAS1HTR7HTR1ACYP1A2 | |
| SCHEMBL1278421 | 1.00 | PAOX (0.52) | PAOXTBXAS1HTR7HTR1ACYP1A2 | |
| SCHEMBL10597308 | 1.00 | PAOX (0.52) | PAOXTBXAS1HTR7HTR1ACYP1A2 | |
| SCHEMBL10597081 | 1.00 | PAOX (0.52) | PAOXTBXAS1HTR7HTR1ACYP1A2 | |
| SCHEMBL1285649 | 0.98 | PAOX (0.48) | PAOXTBXAS1HTR7HTR1ACYP1A2 | |
| SCHEMBL504157 | 0.92 | SMN1; SMN2 (0.50) | PAOXTBXAS1HTR7HTR1ACYP1A2 | |
| SCHEMBL7113039 | 0.86 | SMN1; SMN2 (0.60) | PAOXTBXAS1HTR1ACYP1A2MAPK1 | |
| SCHEMBL1275571 | 0.84 | SMN1; SMN2 (0.62) | TBXAS1HTR1ACYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL6473449 | 0.83 | GLA (0.42) | PAOXTBXAS1HTR7HTR1ACYP1A2 | |
| SCHEMBL19412256 | 0.82 | SMN1; SMN2 (0.66) | CYP1A2MAPK1SMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2625217-B1 | CHAIN-EXTENDED POLYSILOXANE CROSSLINKERS WITH DANGLING HYDROPHILIC POLYMER CHAINS | NOVARTIS AG (CH) | 2018-07-04 | — | — | EP | claimed |
| EP-2625218-B1 | WATER-PROCESSABLE SILICONE-CONTAINING PREPOLYMERS AND USES THEREOF | NOVARTIS AG (CH) | 2018-04-25 | — | — | EP | claimed |
| EP-2598937-B1 | AMPHIPHILIC POLYSILOXANE PREPOLYMERS AND USES THEREOF | NOVARTIS AG (CH) | 2016-06-29 | — | — | EP | claimed |
| US-20120088861-A1 | WATER-PROCESSABLE SILICONE-CONTAINING PREPOLYMERS AND USES THEREOF | ALCON INC. (CH) | 2012-04-12 | — | — | US | claimed |
| US-9684095-B2 | Hydrophilized carbosiloxane vinylic monomers | NOVARTIS AG (CH) | 2017-06-20 | — | — | US | disclosed |
| US-9637582-B2 | Polymerizable polysiloxanes with hydrophilic substituents | NOVARTIS AG (CH) | 2017-05-02 | — | — | US | disclosed |
| US-9500775-B2 | Actinically-crosslinkable amphiphilic prepolymers | NOVARTIS AG (CH) | 2016-11-22 | — | — | US | disclosed |
| US-20160090432-A1 | POLYMERIZABLE POLYSILOXANES WITH HYDROPHILIC SUBSTITUENTS | ALCON INC. (CH) | 2016-03-31 | — | — | US | disclosed |
| US-20150369962-A1 | ACTINICALLY-CROSSLINKABLE AMPHIPHILIC PREPOLYMERS | ALCON INC. (CH) | 2015-12-24 | — | — | US | disclosed |
| US-9187601-B2 | Water-processable silicone-containing prepolymers and uses thereof | NOVARTIS AG (CH) | 2015-11-17 | — | — | US | disclosed |
| US-20150309210-A1 | HYDROPHILIZED CARBOSILOXANE VINYLIC MONOMERS | ALCON INC. (CH) | 2015-10-29 | — | — | US | disclosed |
| US-9103965-B2 | Amphiphilic siloxane-containing vinylic monomers and uses thereof | NOVARTIS AG (CH) | 2015-08-11 | — | — | US | disclosed |
| US-20120088861-A1 | WATER-PROCESSABLE SILICONE-CONTAINING PREPOLYMERS AND USES THEREOF | ALCON INC. (CH) | 2012-04-12 | — | — | US | disclosed |
| US-20110063567-A1 | PREPOLYMERS SUITABLE FOR MAKING ULTRA-VIOLET ABSORBING CONTACT LENSES | ALCON INC. (CH) | 2011-03-17 | — | — | US | disclosed |
| US-7384984-B2 | Reactive hydrophilic oligomers | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2008-06-10 | — | — | US | disclosed |
| US-7074858-B2 | Reactive oligomers | HEILMANN STEVEN M | 2006-07-11 | — | — | US | disclosed |
| US-7015286-B2 | Reactive oligomers | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-03-21 | — | — | US | disclosed |
| US-20050131148-A1 | Reactive hydrophilic oligomers | 3M INNOVATIVE PROPERTIES COMPANY | 2005-06-16 | — | — | US | disclosed |
| US-20040059044-A1 | Oligomeric dyes and use thereof | 3M INNOVATIVE PROPERTIES COMPANY | 2004-03-25 | — | — | US | disclosed |
| US-20030212210-A1 | Reactive oligomers | 3M INNOVATIVE PROPERTIES COMPANY | 2003-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150309210-A1 | HYDROPHILIZED CARBOSILOXANE VINYLIC MONOMERS | VCL, MACF1, HCAR1 | PAOX 295/4885TBXAS1 1697/4885HTR7 468/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.