Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12595149 | 0.82 | LMNA (0.38) | MEN1KMT2ALMNAPOLBNPC1 | |
| SCHEMBL12595150 | 0.82 | LMNA (0.41) | MEN1KMT2ALMNAPOLBNPC1 | |
| SCHEMBL23975266 | 0.79 | POLB (0.36) | MEN1KMT2ALMNAPOLBALDH1A1 | |
| SCHEMBL1145497 | 0.79 | — | — | |
| SCHEMBL18413373 | 0.79 | — | — | |
| SCHEMBL18513575 | 0.79 | — | — | |
| SCHEMBL12448236 | 0.78 | MEN1 (0.40) | MEN1KMT2ALMNAPOLBALDH1A1 | |
| SCHEMBL7477442 | 0.77 | PDK1 (0.44) | MEN1KMT2ALMNAPOLBNPC1 | |
| SCHEMBL7477449 | 0.77 | PDK1 (0.44) | MEN1KMT2ALMNAPOLBNPC1 | |
| SCHEMBL997953 | 0.77 | TSHR (0.41) | MEN1KMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7888536-B2 | Selective and specific preparation of discrete PEG compounds | QUANTA BIODESIGN, LTD. (US) | 2011-02-15 | — | — | US | disclosed |