SCHEMBL997953

SCHEMBL997953

COCC(COC)OCC1CO1

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
ALDH1A1 P00352 8/20 0.40
TDP1 Q9NUW8 2/20 0.38
MAPK1 P28482 1/20 0.38
TP53 P04637 3/20 0.34
MAPT P10636 2/20 0.34
HPGD P15428 2/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
HIF1A Q16665 2/20 0.34
CYP1A2 P05177 1/20 0.34
PPARG P37231 1/20 0.34
GLA P06280 1/20 0.32
CYP3A4 P08684 1/20 0.31
PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12133976 0.90 SMN1; SMN2 (0.41) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL23369241 0.89 SMN1; SMN2 (0.42) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL7896839 0.88 SMN1; SMN2 (0.44) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL24419519 0.81
SCHEMBL16078926 0.81 ALDH1A1 (0.39) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL996341 0.81 TSHR (0.40) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL36444 0.80 ALDH1A1 (0.50) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL22592522 0.80 ALDH1A1 (0.50) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL17011976 0.80 ALDH1A1 (0.50) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL995470 0.80 SMN1; SMN2 (0.44) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4477687-B1 IMMUNOLOGICALLY INACTIVE POLY(ETHYLENE GLYCOL) POLYMER DERIVATIVES AND BIOCONJUGATES THEREOF FOR USE AS ALTERNATIVE IN PEGYLATED THERAPEUTICS, PROCESSES FOR THEIR PREPARATION AND THEIR USE UNIV MAINZ JOHANNES GUTENBERG (DE) 2025-12-17 EP disclosed
EP-4477687-A1 IMMUNOLOGICALLY INACTIVE POLY(ETHYLENE GLYCOL) POLYMER DERIVATIVES AND BIOCONJUGATES THEREOF FOR USE AS ALTERNATIVE IN PEGYLATED THERAPEUTICS, PROCESSES FOR THEIR PREPARATION AND THEIR USE Johannes Gutenberg-Universität Mainz (DE) 2024-12-18 EP disclosed
US-20170369700-A1 EPOXY RESIN COMPOSITION, AND FILM, PREPREG, AND FIBER-REINFORCED PLASTIC USING SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2017-12-28 US disclosed
US-8865392-B2 Photosensitive resin composition and cured product thereof NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2014-10-21 US disclosed
US-20140302430-A1 EPOXY FORMULATIONS AND PROCESSES FOR FABRICATION OF RELIEF PATTERNS ON LOW SURFACE ENERGY SUBSTRATES MICROCHEM CORP. (US) 2014-10-09 US disclosed
US-8648022-B2 Lubricating oil for refrigerator and hydraulic fluid composition for refrigerator using the same IDEMITSU KOSAN CO., LTD. (JP) 2014-02-11 US disclosed
US-8648146-B2 Activated solid support and method GE HEALTHCARE BIO-SCIENCES AB (SE) 2014-02-11 US disclosed
US-8648146-B2 Activated solid support and method GE HEALTHCARE BIO-SCIENCES AB (SE) 2014-02-11 US disclosed
US-20130108961-A1 Photosensitive Resin Composition And Cured Product Thereof NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2013-05-02 US disclosed
US-20120245301-A1 ACTIVATED SOLID SUPPORT AND METHOD GE HEALTHCARE BIO-SCIENCES AB (SE) 2012-09-27 US disclosed
US-5928393-A ESTERIFIED, ALKOXYLATED TERTIARY AMINE COMPOUND; DETERGENT ANTISLUDGE/ANTIDEPOSIT AGENT FOR INTERNAL COMBUSTION ENGINES NIPPON OIL CO., LTD. (JP) 1999-07-27 US disclosed
US-5837016-A ETHERIFIED (POLY)OXYALKYLENE GLYCOL CONTAINING AN AMIDE GROUP; INTERNAL COMBUSTION ENGINE ANTIDEPOSIT AGENTS NIPPON OIL CO., LTD. (JP) 1998-11-17 US disclosed
US-5755833-A URETHANE COMPOUND; ANTIDEPOSIT, ANTISLUDGING AGENT; GASOLINE NIPPON OIL CO., LTD. (JP) 1998-05-26 US disclosed
EP-0819753-A1 Fuel additive NIPPON OIL CO. LTD. (JP) 1998-01-21 EP disclosed
EP-0801128-A1 Fuel additive NIPPON OIL CO. LTD. (JP) 1997-10-15 EP disclosed
EP-0723985-A1 Fuel additive NIPPON OIL CO. LTD. (JP) 1996-07-31 EP disclosed
US-5536881-A Lubricating oil for compression-type refrigerators and polyoxyalkylene glycol derivatives IDEMITSU KOSAN CO., LTD. (JP) 1996-07-16 US disclosed
US-5269955-A 1,1,1,2-tetrafluoroethylene refrigerant IDEMITSU KOSAN CO., LTD. (JP) 1993-12-14 US disclosed
EP-0397037-B1 Use of polyoxyalkylene glycol derivative in lubricating oil for compression-type refrigerators. IDEMITSU KOSAN CO (JP) 1993-11-03 EP disclosed
EP-0397037-A2 Use of polyoxyalkylene glycol derivative in lubricating oil for compression-type refrigerators. IDEMITSU KOSAN COMPANY LIMITED (JP) 1990-11-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120245301-A1 ACTIVATED SOLID SUPPORT AND METHOD OSTC, HLCS, SPR TSHR 1834/4885SMN1; SMN2 4757/4885ALDH1A1 3502/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.