SCHEMBL12866303

SCHEMBL12866303

Oc1ccc(/C=C2\Oc3ccccc3N2CCc2ccccc2)cc1O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EP300 Q09472 1/20 0.44
MEN1 O00255 4/20 0.41
KMT2A Q03164 4/20 0.41
TDP1 Q9NUW8 3/20 0.41
MAPK1 P28482 3/20 0.41
EGFR P00533 3/20 0.41
IGF1R P08069 2/20 0.41
HDAC3 O15379 1/20 0.41
STK17B O94768 1/20 0.41
RECQL P46063 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC7 Q8WUI4 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC10 Q969S8 1/20 0.41
HDAC11 Q96DB2 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
HDAC9 Q9UKV0 1/20 0.41
HDAC5 Q9UQL6 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12866302 0.83 EP300 (0.37) EP300MEN1KMT2ATDP1MAPK1
SCHEMBL13005251 0.82 SIGMAR1 (0.39) EP300MEN1KMT2AMAPK1EGFR
SCHEMBL28064646 0.73 SIGMAR1 (0.63) MEN1KMT2AGSK3BGAACASP3
SCHEMBL12880707 0.71 MEN1 (0.41) EP300MEN1KMT2ATDP1MAPK1
SCHEMBL12866282 0.68 CXCL12 (0.39) EP300MEN1KMT2ATDP1MAPK1
SCHEMBL19091685 0.67 SIGMAR1 (0.47) MEN1KMT2ATDP1HDAC3HDAC6
SCHEMBL18500034 0.64 SIGMAR1 (0.44) MEN1KMT2ATDP1SIGMAR1ALDH1A1
SCHEMBL8847886 0.62 CYP3A4 (0.56) MEN1KMT2ATDP1MAPK1EGFR
SCHEMBL9682424 0.62 CYP3A4 (0.56) MEN1KMT2ATDP1MAPK1EGFR
SCHEMBL490517 0.60 KDM4E (0.50) EP300MEN1KMT2ATDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8338701-B2 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2012-12-25 US disclosed
US-8338700-B2 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2012-12-25 US disclosed
US-20110030801-A1 Dye-Sensitized Photoelectric Conversion Device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-02-10 US disclosed
US-20110031446-A1 Dye-Sensitized Photoelectric Conversion Device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-02-10 US disclosed
US-7851701-B2 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2010-12-14 US disclosed