Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | LCK | P06239 | 3/20 | 0.56 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.56 |
| ▸ | TTR | P02766 | 3/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.56 |
| ▸ | MMP1 | P03956 | 3/20 | 0.56 |
| ▸ | MMP2 | P08253 | 3/20 | 0.56 |
| ▸ | MMP9 | P14780 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | APP | P05067 | 2/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8847886 | 1.00 | CYP3A4 (0.56) | CYP3A4ALDH1A1RECQLHSD17B10ALOX15 | |
| SCHEMBL154597 | 0.81 | TAAR1 (0.53) | AKR1B10AKR1B1MMP1MMP2MMP9 | |
| SCHEMBL154598 | 0.81 | TAAR1 (0.53) | AKR1B10AKR1B1MMP1MMP2MMP9 | |
| SCHEMBL28313741 | 0.80 | ALDH1A1 (0.70) | CYP3A4ALDH1A1RECQLHSD17B10ALOX15 | |
| SCHEMBL28313721 | 0.78 | ALDH1A1 (0.68) | CYP3A4ALDH1A1RECQLHSD17B10ALOX15 | |
| SCHEMBL22577492 | 0.78 | ALOX5 (0.64) | CYP3A4ALDH1A1RECQLHSD17B10ALOX15 | |
| SCHEMBL30742787 | 0.78 | GPR52 (0.48) | RECQLAKR1B10AKR1B1MMP1MMP2 | |
| SCHEMBL108688 | 0.78 | GPR52 (0.48) | RECQLAKR1B10AKR1B1MMP1MMP2 | |
| SCHEMBL108687 | 0.78 | GPR52 (0.48) | RECQLAKR1B10AKR1B1MMP1MMP2 | |
| SCHEMBL16743482 | 0.76 | ALOX5 (0.60) | CYP3A4ALDH1A1RECQLHSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0466198-A1 | A lipoxygenase inhibitor | GREEN CROSS CORPORATION (JP) | 1992-01-15 | — | — | EP | disclosed |
| EP-0466197-A1 | A lipoxygenase inhibitor | GREEN CROSS CORPORATION (JP) | 1992-01-15 | — | — | EP | disclosed |
| EP-0464859-A1 | A lipoxygenase inhibitor | GREEN CROSS CORPORATION (JP) | 1992-01-08 | — | — | EP | disclosed |
| EP-0464858-A1 | A lipoxygenase inhibitor | GREEN CROSS CORPORATION (JP) | 1992-01-08 | — | — | EP | disclosed |
| US-4733002-A | Lipoxygenase inhibitor | GREEN CROSS CORPORATION (JP) | 1988-03-22 | — | — | US | disclosed |
| EP-0163270-A2 | A lipoxygenase inhibitor | GREEN CROSS CORPORATION (JP) | 1985-12-04 | — | — | EP | disclosed |