SCHEMBL12866309

SCHEMBL12866309

CN1C(=O)C(=C/C=C/c2cccc(O)c2O)C(=O)N(C)C1=O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IAPP P10997 4/20 0.45
APP P05067 1/20 0.43
NOX4 Q9NPH5 5/20 0.41
NOX1 Q9Y5S8 5/20 0.41
ERN1 O75460 1/20 0.41
KMT2A Q03164 2/20 0.41
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 1/20 0.41
MAPT P10636 1/20 0.41
MAPK1 P28482 1/20 0.41
HTT P42858 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
CDK4 P11802 1/20 0.39
CCND1 P24385 1/20 0.39
XDH P47989 1/20 0.39
RELA Q04206 1/20 0.38
POLB P06746 1/20 0.37
GAA P10253 1/20 0.37
RAB9A P51151 1/20 0.37
BACE1 P56817 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12866315 0.82 NOX4 (0.54) NOX4NOX1ERN1KMT2AKDM4E
SCHEMBL14712872 0.78 MAPT (0.46) APPKMT2AKDM4EALDH1A1MAPT
SCHEMBL14712881 0.77 ALDH1A1 (0.45) APPKMT2AKDM4EALDH1A1MAPT
SCHEMBL14713053 0.75 NR1H3 (0.49) APPKMT2AKDM4EALDH1A1MAPT
SCHEMBL14712998 0.74 APP (0.52) APPKMT2AKDM4EALDH1A1MAPT
SCHEMBL13712701 0.73 APP (0.61) APPKMT2AKDM4EALDH1A1MAPT
SCHEMBL5820790 0.72 CDK4 (0.70) IAPPNOX4ERN1KDM4EALDH1A1
SCHEMBL14713047 0.72 APP (0.60) APPKMT2AKDM4EALDH1A1MAPT
SCHEMBL12866313 0.72 XDH (0.59) KMT2AKDM4EALDH1A1MAPTNPSR1
SCHEMBL14712999 0.72 APP (0.46) APPKMT2AKDM4EALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8338700-B2 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2012-12-25 US disclosed
US-8338700-B2 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2012-12-25 US disclosed
US-8338701-B2 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2012-12-25 US disclosed
US-8338701-B2 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2012-12-25 US disclosed
US-20110030801-A1 Dye-Sensitized Photoelectric Conversion Device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-02-10 US disclosed
US-20110030801-A1 Dye-Sensitized Photoelectric Conversion Device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-02-10 US disclosed
US-20110031446-A1 Dye-Sensitized Photoelectric Conversion Device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-02-10 US disclosed
US-20110031446-A1 Dye-Sensitized Photoelectric Conversion Device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-02-10 US disclosed
US-7851701-B2 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2010-12-14 US disclosed
US-7851701-B2 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2010-12-14 US disclosed