Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | PPARG | P37231 | 3/20 | 0.63 |
| ▸ | BLM | P54132 | 2/20 | 0.63 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.63 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.63 |
| ▸ | THRB | P10828 | 9/20 | 0.57 |
| ▸ | THRA | P10827 | 6/20 | 0.57 |
| ▸ | PCNA | P12004 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.57 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.57 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.57 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | GABRP | O00591 | 1/20 | 0.57 |
| ▸ | GABRD | O14764 | 1/20 | 0.57 |
| ▸ | F2 | P00734 | 1/20 | 0.57 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12866348 | 0.90 | MEN1 (0.78) | MEN1KMT2APPARGBLMNR1I2 | |
| SCHEMBL12866370 | 0.88 | NR1I2 (0.62) | MEN1KMT2APPARGBLMNR1I2 | |
| SCHEMBL12866377 | 0.88 | THRB (0.58) | MEN1KMT2APPARGBLMNR1I2 | |
| SCHEMBL9647408 | 0.88 | THRB (0.52) | MEN1KMT2APPARGBLMNR1I2 | |
| SCHEMBL951158 | 0.88 | THRB (0.52) | MEN1KMT2APPARGBLMNR1I2 | |
| Diiodothyronine SCHEMBL677645 | 0.87 | MEN1 (0.78) | MEN1KMT2APPARGBLMNR1I2 | |
| Diiodothyronine SCHEMBL31613058 | 0.87 | MEN1 (0.78) | MEN1KMT2APPARGBLMNR1I2 | |
| Diiodothyronine SCHEMBL29374527 | 0.87 | MEN1 (0.78) | MEN1KMT2APPARGBLMNR1I2 | |
| Diiodothyronine SCHEMBL29410661 | 0.87 | MEN1 (0.78) | MEN1KMT2APPARGBLMNR1I2 | |
| Diiodothyronine SCHEMBL935895 | 0.87 | MEN1 (0.78) | MEN1KMT2APPARGBLMNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110028554-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING DIIODOTHYRONINE AND THEIR THERAPEUTIC USE | UNIVERSITE JOSEPH FOURIER (FR) | 2011-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028554-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING DIIODOTHYRONINE AND THEIR THERAPEUTIC USE | TPO, HSD3B2, THRB | MEN1 692/4885KMT2A 2483/4885PPARG 189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.