Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | THRA | P10827 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | PPARG | P37231 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | GABRP | O00591 | 1/20 | 0.52 |
| ▸ | GABRD | O14764 | 1/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | PCNA | P12004 | 1/20 | 0.52 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.52 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.52 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.52 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.52 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.52 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9647408 | 1.00 | THRB (0.52) | THRBMEN1KMT2ATHRALMNA | |
| Hydrochloric Acid SCHEMBL9662459 | 0.99 | ALDH1A1 (0.53) | THRBMEN1KMT2ATHRALMNA | |
| Hydrochloric Acid SCHEMBL7673388 | 0.99 | ALDH1A1 (0.53) | THRBMEN1KMT2ATHRALMNA | |
| SCHEMBL12866354 | 0.88 | MEN1 (0.63) | THRBMEN1KMT2ATHRALMNA | |
| SCHEMBL3683264 | 0.87 | THRB (0.52) | THRBMEN1KMT2ATHRALMNA | |
| SCHEMBL8160664 | 0.87 | THRB (0.51) | THRBMEN1KMT2ATHRALMNA | |
| SCHEMBL3683267 | 0.87 | THRB (0.52) | THRBMEN1KMT2ATHRALMNA | |
| SCHEMBL12866377 | 0.87 | THRB (0.58) | THRBMEN1KMT2ATHRALMNA | |
| SCHEMBL27294832 | 0.87 | THRB (0.53) | THRBMEN1KMT2ATHRALMNA | |
| Melevodopa SCHEMBL8470037 | 0.86 | ALOX15 (0.66) | MEN1KMT2ALMNAPPARGCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11053249-B2 | Proteasome inhibiting β-lactam prodrugs useful for the treatment of cancer and neurodegenerative disorders | PHILIPPE YVES-REMY SIMON (FR) | 2021-07-06 | — | — | US | claimed |
| US-5155229-A | Inhibit cholesterol biosynthesis, radioimmunoassay of pravastatin and its derivatives | E. R. SQUIBB & SONS, INC. (US) | 1992-10-13 | — | — | US | claimed |
| US-4857522-A | Derivatives of pravastatin for inhibiting cholesterol biosynthesis | E. R. SQUIBB & SONS, INC. (US) | 1989-08-15 | — | — | US | claimed |
| US-20260115330-A1 | RADIOPAQUE MULTI-ARM POLYMERS FOR MEDICAL APPLICATIONS | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2026-04-30 | — | — | US | disclosed |
| US-20260049178-A1 | CROSSLINKING AGENTS AND MEDICAL HYDROGELS FORMED THEREFROM | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2026-02-19 | — | — | US | disclosed |
| WO-2025024422-A1 | CROSSLINKING AGENTS AND MEDICAL HYDROGELS FORMED THEREFROM | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2025-01-30 | — | — | WO | disclosed |
| US-20240335568-A1 | RADIOPAQUE POLYSACCHARIDE HYDROGELS AND METHODS OF MAKING THE SAME | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2024-10-10 | — | — | US | disclosed |
| US-11702452-B2 | Process for making arylomycin ring analogs | GENENTECH, INC. (US) | 2023-07-18 | — | — | US | disclosed |
| US-11702452-B2 | Process for making arylomycin ring analogs | GENENTECH, INC. (US) | 2023-07-18 | — | — | US | disclosed |
| US-11702452-B2 | Process for making arylomycin ring analogs | GENENTECH, INC. (US) | 2023-07-18 | — | — | US | disclosed |
| US-20220056078-A1 | PROCESS FOR MAKING ARYLOMYCIN RING ANALOGS | GENENTECH, INC. (US) | 2022-02-24 | — | — | US | disclosed |
| WO-1999006433-A1 | COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | ELAN PHARMACEUTICALS, INC. (US) | 1999-02-11 | — | — | WO | disclosed |
| WO-1998022493-A2 | N-(ARYL/HETEROARYL) AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, AND METHODS FOR INHIBITING β-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS BY USE OF SUCH COMPOUNDS | ELAN PHARMACEUTICALS, INC. (US) | 1998-05-28 | — | — | WO | disclosed |
| US-5155229-A | Inhibit cholesterol biosynthesis, radioimmunoassay of pravastatin and its derivatives | E. R. SQUIBB & SONS, INC. (US) | 1992-10-13 | — | — | US | disclosed |
| US-5096694-A | Chloromethyl- and radioactive iodine substituted hydroxygonane derivatives | IRE-CELLTARG S.A. (BE) | 1992-03-17 | — | — | US | disclosed |
| US-5047549-A | Radioimmunoassay | E. R. SQUIBB & SONS, INC. (US) | 1991-09-10 | — | — | US | disclosed |
| US-4857522-A | Derivatives of pravastatin for inhibiting cholesterol biosynthesis | E. R. SQUIBB & SONS, INC. (US) | 1989-08-15 | — | — | US | disclosed |
| EP-0310645-A1 | COMPOUNDS USEFUL PARTICULARLY FOR RADIOTHERAPY OR IMAGING OF CANCER. | IRECELLTARG S A (BE) | 1989-04-12 | — | — | EP | disclosed |
| WO-1988007986-A2 | COMPOUNDS USEFUL PARTICULARLY FOR RADIOTHERAPY OR IMAGING OF CANCER | IRE-CELLTARG S.A. (BE) | 1988-10-20 | — | — | WO | disclosed |
| EP-0048159-A2 | Novel carboxyalkyl peptides and thioethers and ethers of peptides as antihypertensive agents | UNIVERSITY OF MIAMI (US) | 1982-03-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240335568-A1 | RADIOPAQUE POLYSACCHARIDE HYDROGELS AND METHODS OF MAKING THE SAME | CD44, ALG1, CA13 | THRB 4074/4885MEN1 1073/4885KMT2A 3066/4885 |
| US-20260115330-A1 | RADIOPAQUE MULTI-ARM POLYMERS FOR MEDICAL APPLICATIONS | KLK3, BRDT, BPHL | THRB 955/4885MEN1 1567/4885KMT2A 2276/4885 |
| US-20260049178-A1 | CROSSLINKING AGENTS AND MEDICAL HYDROGELS FORMED THEREFROM | NPPA, MACF1, IGF1R | THRB 651/4885MEN1 1139/4885KMT2A 774/4885 |
| US-11702452-B2 | Process for making arylomycin ring analogs | RRS1, GLRA1, MRPL21 | THRB 638/4885MEN1 3392/4885KMT2A 3875/4885 |
| US-11053249-B2 | Proteasome inhibiting β-lactam prodrugs useful for the treatment of cancer and neurodegenerative disorders | PSMB5, PSMB1, PSMB11 | THRB 3241/4885MEN1 1547/4885KMT2A 2078/4885 |
| US-20220056078-A1 | PROCESS FOR MAKING ARYLOMYCIN RING ANALOGS | RRS1, GLRA1, MRPL21 | THRB 638/4885MEN1 3392/4885KMT2A 3875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.