Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.57 |
| ▸ | PPARG | P37231 | 4/20 | 0.57 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.57 |
| ▸ | BLM | P54132 | 2/20 | 0.57 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 8/20 | 0.54 |
| ▸ | LMNA | P02545 | 5/20 | 0.54 |
| ▸ | THRA | P10827 | 5/20 | 0.54 |
| ▸ | USP2 | O75604 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | TTR | P02766 | 2/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12866377 | 0.90 | THRB (0.58) | MEN1KMT2APPARGNR1I2BLM | |
| SCHEMBL677606 | 0.86 | MEN1 (0.74) | MEN1KMT2APPARGNR1I2BLM | |
| SCHEMBL9619480 | 0.86 | MEN1 (0.74) | MEN1KMT2APPARGNR1I2BLM | |
| SCHEMBL2139921 | 0.86 | MEN1 (0.74) | MEN1KMT2APPARGNR1I2BLM | |
| SCHEMBL12866348 | 0.86 | MEN1 (0.78) | MEN1KMT2APPARGNR1I2BLM | |
| SCHEMBL7273637 | 0.85 | ESR1 (0.55) | ALDH1A1PTGS2MIFPCNA | |
| SCHEMBL8369339 | 0.84 | THRB (0.76) | MEN1KMT2APPARGNR1I2BLM | |
| SCHEMBL8369341 | 0.84 | THRB (0.76) | MEN1KMT2APPARGNR1I2BLM | |
| Hydrochloric Acid SCHEMBL8825443 | 0.83 | THRB (0.74) | MEN1KMT2APPARGNR1I2BLM | |
| Hydrochloric Acid SCHEMBL8825447 | 0.83 | THRB (0.74) | MEN1KMT2APPARGNR1I2BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110028554-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING DIIODOTHYRONINE AND THEIR THERAPEUTIC USE | UNIVERSITE JOSEPH FOURIER (FR) | 2011-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028554-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING DIIODOTHYRONINE AND THEIR THERAPEUTIC USE | TPO, HSD3B2, THRB | MEN1 692/4885KMT2A 2483/4885PPARG 189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.