SCHEMBL1286852

SCHEMBL1286852

O=C(O)c1ccccc1C(=O)OCCOc1ccccc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.71
RAB9A P51151 5/20 0.71
NPC1 O15118 4/20 0.71
SMN1; SMN2 Q16637 4/20 0.71
KMT2A Q03164 3/20 0.71
MEN1 O00255 2/20 0.71
KDM4E B2RXH2 1/20 0.71
HPGD P15428 1/20 0.71
NFKB1 P19838 1/20 0.71
NFKB2 Q00653 1/20 0.71
RELA Q04206 1/20 0.71
HSD17B10 Q99714 1/20 0.71
TSHR P16473 4/20 0.56
PKM P14618 1/20 0.56
THRB P10828 1/20 0.54
MMP1 P03956 1/20 0.54
MMP12 P39900 1/20 0.54
TDP1 Q9NUW8 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
MAPT P10636 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11327387 0.95 ALDH1A1 (0.78) ALDH1A1RAB9ANPC1SMN1; SMN2KMT2A
SCHEMBL11328318 0.92 ALDH1A1 (0.60) ALDH1A1RAB9ANPC1SMN1; SMN2KMT2A
SCHEMBL10577928 0.91 ALDH1A1 (0.60) ALDH1A1RAB9ANPC1SMN1; SMN2KMT2A
SCHEMBL3302489 0.89 ALDH1A1 (0.69) ALDH1A1RAB9ANPC1SMN1; SMN2KMT2A
SCHEMBL28492073 0.87 ALDH1A1 (0.67) ALDH1A1RAB9ANPC1SMN1; SMN2KMT2A
SCHEMBL11328321 0.86 ALDH1A1 (0.66) ALDH1A1RAB9ANPC1SMN1; SMN2KMT2A
SCHEMBL8595155 0.85 RAB9A (0.69) ALDH1A1RAB9ANPC1SMN1; SMN2KMT2A
SCHEMBL11823795 0.85 RAB9A (0.69) ALDH1A1RAB9ANPC1SMN1; SMN2KMT2A
SCHEMBL11315331 0.84 TSHR (0.76) ALDH1A1RAB9ANPC1SMN1; SMN2KMT2A
Ethylene Glycol SCHEMBL8006697 0.84 ALDH1A1 (0.62) ALDH1A1RAB9ANPC1SMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11820844-B2 Charge-modified particles and methods of making the same 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-11-21 US disclosed
US-11492495-B2 Modified aluminum nitride particles and methods of making the same 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-11-08 US disclosed
CN-109312201-B Nanoparticle-filled barrier adhesive compositions 3M创新有限公司 2021-12-07 CN disclosed
CN-111886316-B Charge-modified particles and methods of making the same 3M创新有限公司 2021-07-09 CN disclosed
EP-3768794-B1 CHARGE-MODIFIED PARTICLES AND METHODS OF MAKING THE SAME 3M INNOVATIVE PROPERTIES CO (US) 2021-04-28 EP disclosed
EP-3768794-A2 CHARGE-MODIFIED PARTICLES AND METHODS OF MAKING THE SAME 3M Innovative Properties Company (US) 2021-01-27 EP disclosed
EP-3768655-A1 MODIFIED ALUMINUM NITRIDE PARTICLES AND METHODS OF MAKING THE SAME 3M Innovative Properties Company (US) 2021-01-27 EP disclosed
US-10894903-B2 Nanoparticle filled barrier adhesive compositions 3M INNOVATIVE PROPERTIES COMPANY (US) 2021-01-19 US disclosed
US-20210009811-A1 MODIFIED ALUMINUM NITRIDE PARTICLES AND METHODS OF MAKING THE SAME 3M INNOVATIVE PROPERTIES COMPANY 2021-01-14 US disclosed
US-20210002137-A1 CHARGE-MODIFIED PARTICLES AND METHODS OF MAKING THE SAME 3M INNOVATIVE PROPERTIES COMPANY 2021-01-07 US disclosed
US-7547467-B2 which are dispersed in acrylic polymer to enhance durability and/or refractive index; colloidal titania or zirconia; monophthalate ester (phthalic acid mono-(2-acryloxy-ethyl) ester); a monocarboxylic acid having oxyalkylene groups (2-(2-methoxyethoxy) acetic acid); flat panel displays 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-06-16 US disclosed
WO-2008121465-A1 BRIGHTNESS ENHANCING FILM COMPRISING NANOCOMPOSITE STRUCTURE HAVING IMPROVED CRACK RESISTANCE 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-10-09 WO disclosed
WO-2008121465-A1 BRIGHTNESS ENHANCING FILM COMPRISING NANOCOMPOSITE STRUCTURE HAVING IMPROVED CRACK RESISTANCE 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-10-09 WO disclosed
EP-1840096-A1 INTERMEDIATE FILM OF LAMINATED SAFETY GLASS WITH ANTIGLARE FUNCTION AND NOVEL NEODYMIUM COMPOUND Hopnic Laboratory Co., Ltd. (JP) 2007-10-03 EP disclosed
WO-2007059228-A1 BRIGHTNESS ENHANCING FILM AND METHOD OF SURFACE TREATING INORGANIC NANOPARTICLES 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-05-24 WO disclosed
WO-2007059228-A1 BRIGHTNESS ENHANCING FILM AND METHOD OF SURFACE TREATING INORGANIC NANOPARTICLES 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-05-24 WO disclosed
US-20070112097-A1 BRIGHTNESS ENHANCING FILM AND METHODS OF SURFACE TREATING INORGANIC NANOPARTICLES 3M INNOVATIVE PROPERTIES COMPANY 2007-05-17 US disclosed
US-20070112097-A1 BRIGHTNESS ENHANCING FILM AND METHODS OF SURFACE TREATING INORGANIC NANOPARTICLES 3M INNOVATIVE PROPERTIES COMPANY 2007-05-17 US disclosed
US-4273696-A IMPROVE COLD FLEX IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1981-06-16 US disclosed
EP-0002329-A1 Plasticized polyvinylchloride compositions IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1979-06-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210002137-A1 CHARGE-MODIFIED PARTICLES AND METHODS OF MAKING THE SAME PCTP, MBOAT1, CA13 ALDH1A1 3429/4885RAB9A 3661/4885NPC1 3250/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.