Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 9/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | PNP | P00491 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | DHFR | P00374 | 3/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | PI4KA | P42356 | 1/20 | 0.50 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.50 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.50 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.50 |
| ▸ | TK1 | P04183 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL21799342 | 0.99 | XDH (0.97) | XDHMEN1KMT2APNPKDM4E | |
| SCHEMBL27881952 | 0.86 | XDH (0.76) | XDHMEN1KMT2APNPKDM4E | |
| SCHEMBL3761457 | 0.86 | XDH (1.00) | XDHMEN1KMT2APNPPI4KA | |
| SCHEMBL3310025 | 0.86 | XDH (0.76) | XDHMEN1KMT2APNPDHFR | |
| SCHEMBL15542829 | 0.84 | XDH (0.76) | XDHMEN1KMT2APNPTK1 | |
| SCHEMBL8537126 | 0.84 | XDH (1.00) | XDHMEN1KMT2APNP | |
| SCHEMBL3759472 | 0.82 | XDH (0.70) | XDHMEN1KMT2APNPKDM4E | |
| SCHEMBL637360 | 0.81 | XDH (0.67) | XDHMEN1KMT2APNPDHFR | |
| SCHEMBL11610794 | 0.79 | XDH (0.69) | XDHMEN1KMT2APNPTK1 | |
| SCHEMBL1899765 | 0.78 | XDH (0.64) | XDHMEN1KMT2APNPTK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115128195-B | LC-MS/MS detection method for pesticide and veterinary drug residues in animal oil and vegetable oil | 北京市疾病预防控制中心 | 2022-11-15 | — | — | CN | claimed |
| WO-2012047630-A2 | N-ALKYL OR N-ARYL SUBSTITUTED GUANIDE AND BIGUANIDE COMPOUNDS AND METHODS OF THEIR USE | TEINTZE MARTIN (US) | 2012-04-12 | — | — | WO | claimed |
| EP-0794781-A4 | DRUGS TO PREVENT RECURRENT HERPES VIRUS INFECTIONS | UNIV MASSACHUSETTS MEDICAL (US) | 1998-04-22 | — | — | EP | claimed |
| EP-0794781-A1 | DRUGS TO PREVENT RECURRENT HERPES VIRUS INFECTIONS | UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER (US) | 1997-09-17 | — | — | EP | claimed |
| WO-1996020711-A1 | DRUGS TO PREVENT RECURRENT HERPES VIRUS INFECTIONS | UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER (US) | 1996-07-11 | — | — | WO | claimed |
| CN-119998660-A | Compositions and methods for polypeptide analysis | 宽腾矽公司 | 2025-05-13 | — | — | CN | disclosed |
| CN-115504909-A | Benzoylguanidine derivative and preparation method and application thereof | 青岛海洋生物医药研究院 | 2022-12-23 | — | — | CN | disclosed |
| US-11044912-B2 | Branched polymeric biguanide compounds and their uses | CHEN HWANG HSING (US) | 2021-06-29 | — | — | US | disclosed |
| US-10813911-B2 | Methods of treating and/or preventing chronic obstructive pulmonary disease | UNIV BORDEAUX (FR) | 2020-10-27 | — | — | US | disclosed |
| EP-3621952-A1 | METHOD FOR THE PRODUCTION OF PHENYLGUANIDINES OR THE SALTS THEREOF | AlzChem Trostberg GmbH (DE) | 2020-03-18 | — | — | EP | disclosed |
| US-20190373895-A1 | BRANCHED POLYMERIC BIGUANIDE COMPOUNDS AND THEIR USES | CHEN HWANG HSING (US) | 2019-12-12 | — | — | US | disclosed |
| WO-2019010201-A1 | SMALL MOLECULE ADAPTER REGULATED | YALE UNIVERSITY (US) | 2019-01-10 | — | — | WO | disclosed |
| EP-0794781-A4 | DRUGS TO PREVENT RECURRENT HERPES VIRUS INFECTIONS | UNIV MASSACHUSETTS MEDICAL (US) | 1998-04-22 | — | — | EP | disclosed |
| EP-0794781-A4 | DRUGS TO PREVENT RECURRENT HERPES VIRUS INFECTIONS | UNIV MASSACHUSETTS MEDICAL (US) | 1998-04-22 | — | — | EP | disclosed |
| EP-0794781-A1 | DRUGS TO PREVENT RECURRENT HERPES VIRUS INFECTIONS | UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER (US) | 1997-09-17 | — | — | EP | disclosed |
| EP-0794781-A1 | DRUGS TO PREVENT RECURRENT HERPES VIRUS INFECTIONS | UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER (US) | 1997-09-17 | — | — | EP | disclosed |
| US-5646155-A | ADMINISTERING A 9-SUBSTITUTED-N2-PHENYLGUANINE DERIVATIVE | UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER (US) | 1997-07-08 | — | — | US | disclosed |
| US-5646155-A | ADMINISTERING A 9-SUBSTITUTED-N2-PHENYLGUANINE DERIVATIVE | UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER (US) | 1997-07-08 | — | — | US | disclosed |
| WO-1996020711-A1 | DRUGS TO PREVENT RECURRENT HERPES VIRUS INFECTIONS | UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER (US) | 1996-07-11 | — | — | WO | disclosed |
| WO-1996020711-A1 | DRUGS TO PREVENT RECURRENT HERPES VIRUS INFECTIONS | UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER (US) | 1996-07-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11044912-B2 | Branched polymeric biguanide compounds and their uses | PUF60, XRCC6, PCNA | XDH 1954/4885MEN1 975/4885KMT2A 1286/4885 |
| US-20190373895-A1 | BRANCHED POLYMERIC BIGUANIDE COMPOUNDS AND THEIR USES | PUF60, XRCC6, PCNA | XDH 1954/4885MEN1 975/4885KMT2A 1286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.